Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | MARK3 | P27448 | 1/20 | 0.42 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.42 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27449574 | 0.82 | L3MBTL1 (0.54) | L3MBTL1MEN1KMT2AACHEBRD4 | |
| SCHEMBL5958192 | 0.79 | L3MBTL1 (0.51) | L3MBTL1MEN1KMT2AACHEBRD4 | |
| SCHEMBL1196432 | 0.78 | L3MBTL1 (0.62) | L3MBTL1MEN1KMT2AACHEBRD4 | |
| SCHEMBL7004454 | 0.78 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2AACHEBRD4 | |
| SCHEMBL28879342 | 0.78 | L3MBTL1 (0.59) | L3MBTL1MEN1KMT2AACHEBRD4 | |
| SCHEMBL28795466 | 0.78 | L3MBTL1 (0.50) | L3MBTL1MEN1KMT2AACHEBRD4 | |
| SCHEMBL21246901 | 0.77 | L3MBTL1 (0.52) | L3MBTL1MEN1KMT2AACHEBRD4 | |
| SCHEMBL1196430 | 0.76 | L3MBTL1 (0.59) | L3MBTL1MEN1KMT2AACHEBRD4 | |
| SCHEMBL21246906 | 0.76 | L3MBTL1 (0.59) | L3MBTL1MEN1KMT2AACHEBRD4 | |
| SCHEMBL21259294 | 0.76 | L3MBTL1 (0.59) | L3MBTL1MEN1KMT2AACHEBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019153216-A1 | SUBSTITUTED ARYLAMINO ALCOHOL COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 北京梅尔森医药技术开发有限公司 | 2019-08-15 | — | — | WO | disclosed |