Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | MARK3 | P27448 | 1/20 | 0.44 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.44 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27449574 | 0.82 | L3MBTL1 (0.54) | L3MBTL1ACHEMEN1KMT2APIM1 | |
| SCHEMBL3533644 | 0.81 | KMT2A (0.56) | L3MBTL1ACHEMEN1KMT2APIM1 | |
| SCHEMBL29443981 | 0.81 | KMT2A (0.56) | L3MBTL1ACHEMEN1KMT2APIM1 | |
| SCHEMBL28795466 | 0.81 | L3MBTL1 (0.50) | L3MBTL1ACHEMEN1KMT2APIM1 | |
| SCHEMBL7005408 | 0.80 | ALDH1A1 (0.38) | L3MBTL1MEN1KMT2ACREBBP | |
| Formic Acid SCHEMBL29025505 | 0.80 | L3MBTL1 (0.57) | L3MBTL1ACHEMEN1KMT2APIM1 | |
| SCHEMBL5958192 | 0.79 | L3MBTL1 (0.51) | L3MBTL1ACHEMEN1KMT2APIM1 | |
| SCHEMBL21246906 | 0.79 | L3MBTL1 (0.59) | L3MBTL1ACHEMEN1KMT2APIM1 | |
| SCHEMBL21259294 | 0.79 | L3MBTL1 (0.59) | L3MBTL1ACHEMEN1KMT2APIM1 | |
| SCHEMBL1196430 | 0.79 | L3MBTL1 (0.59) | L3MBTL1ACHEMEN1KMT2APIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104363903-A | Phenyl-urea and phenyl-carbamate derivatives as inhibitors of protein aggregation | NEUROPORE THERAPIES INC | 2015-02-18 | — | — | CN | disclosed |
| US-20030105118-A1 | Tricyclic quinazolinediones | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2003-06-05 | — | — | US | disclosed |
| EP-1288216-A1 | TRICYCLIC QUINAZOLINEDIONES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2003-03-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105118-A1 | Tricyclic quinazolinediones | PARP1, PARP11, PARP2 | L3MBTL1 2665/4885ACHE 3205/4885MEN1 3836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.