SCHEMBL21247063

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21250157	0.87	CA1 (0.47)	CA1CA2EGFRKDRITK
	SCHEMBL21247064	0.83	CA1 (0.47)	CA1CA2ITKKDM1AKDM4E
	SCHEMBL1343465	0.76	CA1 (0.69)	CA1CA2ITKKDM4EALDH1A1
	SCHEMBL18317270	0.74	NQO2 (0.42)	KDM4EALDH1A1MEN1KMT2ATSHR
	SCHEMBL25131	0.73	ALDH1A1 (0.46)	KDM4EALDH1A1TSHRCYP1A2CYP1B1
	SCHEMBL29131409	0.73	CA1 (0.65)	CA1CA2KDM4EALDH1A1TSHR
	SCHEMBL3632654	0.73	CA1 (0.65)	CA1CA2KDM4EALDH1A1TSHR
	SCHEMBL18317453	0.72	ESR1 (0.35)	CA1CA2KDM4EALDH1A1MEN1
	SCHEMBL1168013	0.72	ALDH1A1 (0.44)	KDM4EALDH1A1MEN1KMT2ATSHR
	SCHEMBL22042786	0.72	CA1 (0.46)	CA1CA2ENPP3CYP19A1CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.