Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21250157 | 0.87 | CA1 (0.47) | CA1CA2CYP19A1CYP17A1CYP11B1 | |
| SCHEMBL21247063 | 0.83 | CA1 (0.47) | CA1CA2CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL22042786 | 0.79 | CA1 (0.46) | CA1CA2CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL1344052 | 0.74 | CA1 (0.67) | CA1CA2CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9958196 | 0.74 | ESR1 (0.40) | CYP1A2ALDH1A1 | |
| SCHEMBL2387979 | 0.74 | CYP1A2 (0.42) | CYP1A1CYP1A2CYP1B1XDHCYP2A6 | |
| SCHEMBL18317758 | 0.74 | NQO2 (0.42) | CYP1A2CYP2A6KDM4EALDH1A1 | |
| SCHEMBL25131 | 0.73 | ALDH1A1 (0.46) | CYP1A2CYP1B1CYP2A6KDM4EALDH1A1 | |
| SCHEMBL12320895 | 0.73 | CA1 (0.65) | CA1CA2CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL12310187 | 0.73 | CA1 (0.65) | CA1CA2CYP1A1CYP1A2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3749631-B1 | TRIARYLMETHANE COMPOUNDS | MITSUBISHI GAS CHEMICAL CO (JP) | 2024-03-06 | — | — | EP | disclosed |
| CN-111712481-B | triarylmethane compounds | 三菱瓦斯化学株式会社 | 2024-01-16 | — | — | CN | disclosed |
| US-20230391704-A1 | TRIARYLMETHANE COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2023-12-07 | — | — | US | disclosed |
| US-11760712-B2 | Triarylmethane compounds | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2023-09-19 | — | — | US | disclosed |
| US-20210371367-A1 | TRIARYLMETHANE COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2021-12-02 | — | — | US | disclosed |
| EP-3749631-A1 | TRIARYLMETHANE COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2020-12-16 | — | — | EP | disclosed |
| CN-111712481-A | Triarylmethane compounds | 三菱瓦斯化学株式会社 | 2020-09-25 | — | — | CN | disclosed |
| WO-2019154730-A1 | TRIARYLMETHANE COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2019-08-15 | — | — | WO | disclosed |
| WO-2019154727-A1 | TRIARYLMETHANE COMPOUNDS | REUTER CHEMISCHE APPARATEBAU KG (DE) | 2019-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230391704-A1 | TRIARYLMETHANE COMPOUNDS | CBR3, HAX1, HRH3 | CA1 3881/4885CA2 3417/4885CYP1A1 34/4885 |
| US-11760712-B2 | Triarylmethane compounds | CBR3, HAX1, HRH3 | CA1 3881/4885CA2 3417/4885CYP1A1 34/4885 |
| US-20210371367-A1 | TRIARYLMETHANE COMPOUNDS | CBR3, HAX1, HRH3 | CA1 3881/4885CA2 3417/4885CYP1A1 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.