Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.57 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21250392 | 0.84 | VCAM1 (0.51) | VCAM1HCAR3HPGDALDH1A1NPSR1 | |
| SCHEMBL1110902 | 0.83 | HCAR3 (0.70) | VCAM1HCAR3HPGDALDH1A1NPSR1 | |
| SCHEMBL21250378 | 0.82 | HCAR3 (0.51) | VCAM1HCAR3HPGDALDH1A1NPSR1 | |
| SCHEMBL15618541 | 0.81 | HTT (0.64) | VCAM1HCAR3HPGDALDH1A1NPSR1 | |
| SCHEMBL4205262 | 0.79 | VCAM1 (0.59) | VCAM1HCAR3HPGDALDH1A1NPSR1 | |
| SCHEMBL9631242 | 0.75 | VCAM1 (0.58) | VCAM1HCAR3HPGDALDH1A1NPSR1 | |
| SCHEMBL11976724 | 0.75 | VCAM1 (0.57) | VCAM1HCAR3HPGDALDH1A1NPSR1 | |
| SCHEMBL5734347 | 0.75 | VCAM1 (0.68) | VCAM1HPGDALDH1A1NPSR1PKM | |
| SCHEMBL21250405 | 0.74 | VCAM1 (0.53) | VCAM1HCAR3HPGDALDH1A1PKM | |
| SCHEMBL29441708 | 0.74 | VCAM1 (0.53) | VCAM1HCAR3HPGDALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10377748-B2 | Hepatitis B core protein modulators | ASSEMBLY BIOSCIENCES, INC. (US) | 2019-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10377748-B2 | Hepatitis B core protein modulators | HAVCR2, FABP1, MAVS | VCAM1 2825/4885HCAR3 3493/4885HPGD 3375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.