Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NCK1 | P16333 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1832902 | 0.83 | MAPT (0.38) | MAPTRAB9AKDM4ENPC1NQO2 | |
| SCHEMBL11122399 | 0.79 | SMN1; SMN2 (0.49) | MAPTRAB9AKDM4ENPC1GAA | |
| SCHEMBL206103 | 0.75 | SMN1; SMN2 (0.41) | MAPTRAB9AAPPKDM4ENPC1 | |
| SCHEMBL206753 | 0.75 | GFER (0.44) | MAPTRAB9AAPPKDM4ENPC1 | |
| SCHEMBL4718799 | 0.75 | SMN1; SMN2 (0.44) | MAPTRAB9AAPPKDM4ENPC1 | |
| SCHEMBL6601753 | 0.75 | HTT (0.44) | MAPTAPPKDM4EGAADYRK1A | |
| SCHEMBL5006212 | 0.75 | CYP2A6 (0.38) | RAB9ANPC1 | |
| SCHEMBL9722729 | 0.75 | FGFR1 (0.34) | MAPTKDM4ELMNACYP1A2ALDH1A1 | |
| SCHEMBL533470 | 0.75 | CYP1A2 (0.49) | MAPTRAB9AAPPKDM4ENPC1 | |
| SCHEMBL20542591 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344265-A | Amide compound and preparation method and application thereof | 河北大学 | 2024-07-16 | — | — | CN | claimed |
| US-10077261-B2 | Imidazolin-5-one derivative useful as FASN inhibitors for the treatment of cancer | JANSSEN PHARMACEUTICA NV (BE) | 2018-09-18 | — | — | US | claimed |
| EP-2892892-B1 | IMIDAZOLIN-5-ONE DERIVATIVES USEFUL AS FATTY ACID SYNTHASE (FASN) INHIBITORS FOR THE TREATMENT OF CANCER | JANSSEN PHARMACEUTICA NV (BE) | 2017-05-31 | — | — | EP | claimed |
| US-20160002219-A1 | IMIDAZOLIN-5-ONE DERIVATIVE USEFUL AS FASN INHIBITORS FOR THE TREATMENT OF CANCER | JANSSEN PHARMACEUTICA NV (BE) | 2016-01-07 | — | — | US | claimed |
| EP-2892892-A1 | IMIDAZOLIN-5-ONE DERIVATIVES USEFUL AS FATTY ACID SNTHASE (FASN) INHIBITORS FOR!THE TREATMENT OF CANCER | Janssen Pharmaceutica N.V. (BE) | 2015-07-15 | — | — | EP | claimed |
| US-20150099730-A1 | IMIDAZOLIN-5-ONE DERIVATIVE USEFUL AS FASN INHIBITORS FOR THE TREATMENT OF CANCER | JANSSEN PHARMACEUTICA, NV (BE) | 2015-04-09 | — | — | US | claimed |
| WO-2014039769-A1 | IMIDAZOLIN-5-ONE DERIVATIVES USEFUL AS FATTY ACID SNTHASE (FASN) INHIBITORS FOR|THE TREATMENT OF CANCER | JANSSEN PHARMACEUTICA NV (BE) | 2014-03-13 | — | — | WO | claimed |
| US-8293774-B2 | Optically active (R)-aryloxypropionic acid amides and herbicidal composition comprising same | KYUNG NONG CORPORATION (KR) | 2012-10-23 | — | — | US | claimed |
| WO-2011049274-A1 | IMIDAZOLE DERIVATIVES AND COMPOSITIONS FOR TREATING MELANOMA | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-04-28 | — | — | WO | claimed |
| US-20100279871-A1 | OPTICALLY ACTIVE (R)-ARYLOXYPROPIONIC ACID AMIDES AND HERBICIDAL COMPOSITION COMPRISING SAME | KYUNG NONG CORPORATION (KR) | 2010-11-04 | — | — | US | claimed |
| EP-0112285-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1987-03-18 | — | — | EP | claimed |
| EP-0104529-B1 | CATIONIC DYES, THEIR PREPARATION AND THEIR USE IN DYEING SYNTHETIC AND NATURAL MATERIAL | BAYER AG (DE) | 1986-03-05 | — | — | EP | claimed |
| US-4544738-A | FIBER-REACTIVE YELLOW AND ORANGE DYES | BASF AKTIENGESELLSCHAFT (DE) | 1985-10-01 | — | — | US | claimed |
| EP-0053751-B1 | CATIONIC TRIAZENE DYES AND THEIR USE | BAYER AG (DE) | 1984-08-29 | — | — | EP | claimed |
| EP-0104529-A2 | Cationic dyes, their preparation and their use in dyeing synthetic and natural material | BAYER AG (DE) | 1984-04-04 | — | — | EP | claimed |
| US-4432900-A | Cationic dyestuff printing inks | SCOTT PAPER COMPANY (US) | 1984-02-21 | — | — | US | claimed |
| US-4432897-A | Cationic thiadiazolyl triazene dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1984-02-21 | — | — | US | claimed |
| US-4340386-A | ON CELLULOSE WEBS | SCOTT PAPER COMPANY (US) | 1982-07-20 | — | — | US | claimed |
| EP-0053751-A1 | Cationic triazene dyes and their use | BAYER AG (DE) | 1982-06-16 | — | — | EP | claimed |
| US-4143034-A | LIGHTFAST | STERLING DRUG INC. (US) | 1979-03-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279871-A1 | OPTICALLY ACTIVE (R)-ARYLOXYPROPIONIC ACID AMIDES AND HERBICIDAL COMPOSITION COMPRISING SAME | AADAC, DDT, NOTUM | MAPT 641/4885RAB9A 1137/4885APP 2134/4885 |
| US-20150099730-A1 | IMIDAZOLIN-5-ONE DERIVATIVE USEFUL AS FASN INHIBITORS FOR THE TREATMENT OF CANCER | FASN, PLIN1, FABP1 | MAPT 4730/4885RAB9A 1530/4885APP 4722/4885 |
| US-10077261-B2 | Imidazolin-5-one derivative useful as FASN inhibitors for the treatment of cancer | FASN, PLIN1, FABP1 | MAPT 4730/4885RAB9A 1530/4885APP 4722/4885 |
| US-20160002219-A1 | IMIDAZOLIN-5-ONE DERIVATIVE USEFUL AS FASN INHIBITORS FOR THE TREATMENT OF CANCER | FASN, PLIN1, FABP1 | MAPT 4730/4885RAB9A 1530/4885APP 4722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.