Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5540744 | 0.86 | ABL1 (0.44) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL2160767 | 0.85 | RAB9A (0.43) | CYP1A2CYP2C19CYP3A4RAB9ANPC1 | |
| SCHEMBL227271 | 0.81 | KMT2A (0.53) | CYP1A2CYP2C19CYP3A4RAB9ANPC1 | |
| SCHEMBL10820992 | 0.78 | CA2 (0.50) | CYP3A4MAPTKMT2AALDH1A1GAA | |
| SCHEMBL4780658 | 0.77 | NPC1 (0.53) | CYP1A2CYP3A4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5535853 | 0.76 | KDR (0.43) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL8014001 | 0.75 | CA1 (0.49) | CYP3A4ALDH1A1GAATP53LMNA | |
| SCHEMBL970760 | 0.75 | LTA4H (0.45) | CYP1A2MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL212513 | 0.75 | MAPT (0.44) | CYP1A2RAB9ANPC1MEN1MAPT | |
| SCHEMBL4375821 | 0.74 | PDGFRA (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197277-B1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | CHDI FOUNDATION INC (US) | 2021-12-22 | — | — | EP | claimed |
| CN-107441100-B | Compounds for treating ischemia reperfusion injury | 武汉惠康达科技有限公司 | 2020-08-28 | — | — | CN | claimed |
| US-20170283439-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | CCHDI Foundation Inc. (US) | 2017-10-05 | — | — | US | claimed |
| EP-3197277-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | CHDI Foundation, Inc. (US) | 2017-08-02 | — | — | EP | claimed |
| WO-2016033440-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | CHDI FOUNDATION, INC. (US) | 2016-03-03 | — | — | WO | claimed |
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | claimed |
| US-8293774-B2 | Optically active (R)-aryloxypropionic acid amides and herbicidal composition comprising same | KYUNG NONG CORPORATION (KR) | 2012-10-23 | — | — | US | claimed |
| US-20100279871-A1 | OPTICALLY ACTIVE (R)-ARYLOXYPROPIONIC ACID AMIDES AND HERBICIDAL COMPOSITION COMPRISING SAME | KYUNG NONG CORPORATION (KR) | 2010-11-04 | — | — | US | claimed |
| EP-2183213-A2 | OPTICALLY ACTIVE (R)-ARYLOXYPROPIONIC ACID AMIDES AND HERBICIDAL COMPOSITION COMPRISING SAME | Kyung Nong Corporation (KR) | 2010-05-12 | — | — | EP | claimed |
| WO-2009005297-A2 | OPTICALLY ACTIVE (R)-ARYLOXYPROPIONIC ACID AMIDES AND HERBICIDAL COMPOSITION COMPRISING SAME | KYUNG NONG CORPORATION (KR) | 2009-01-08 | — | — | WO | claimed |
| US-20020042501-A1 | Pyrazole compounds | DERMIRA (CANADA), INC. | 2002-04-11 | — | — | US | claimed |
| WO-2001077080-A2 | PYRAZOLE COMPOUNDS HAVING ANTI PROLIFERATIVE ACTIVITY | KINETEK PHARMACEUTICALS, INC. (CA) | 2001-10-18 | — | — | WO | claimed |
| WO-2000012082-A1 | FORMAMIDE COMPOUNDS AS THERAPEUTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2000-03-09 | — | — | WO | claimed |
| US-5310888-A | Calcium detection | MILES INC. (US) | 1994-05-10 | — | — | US | claimed |
| US-4994563-A | Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | claimed |
| EP-0349486-A2 | Azo dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | claimed |
| US-4614804-A | PRINTING, DYEING CELLULOSE | BASF AKTIENGESELLSCHAFT (DE) | 1986-09-30 | — | — | US | claimed |
| US-4525591-A | BROWQN PIGMENT | BASF AKTIENGESELLSCHAFT (DE) | 1985-06-25 | — | — | US | claimed |
| US-4038268-A | DIAZOTIZATION, COUPLING | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-26 | — | — | US | claimed |
| US-4022762-A | Water-soluble acid azo dyestuff containing a N-(p-sulphophenoxyalkyl)-N-alkyl amino group | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1977-05-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279871-A1 | OPTICALLY ACTIVE (R)-ARYLOXYPROPIONIC ACID AMIDES AND HERBICIDAL COMPOSITION COMPRISING SAME | AADAC, DDT, NOTUM | CYP1A2 90/4885CYP2C19 169/4885CYP3A4 259/4885 |
| US-20170283439-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | HTT, HYPK, HSPBP1 | CYP1A2 4836/4885CYP2C19 4805/4885CYP3A4 4877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.