Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 5/20 | 0.38 |
| ▸ | SULT1A1 | P50225 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3125096 | 0.83 | CA2 (0.39) | HTTGAAL3MBTL1DYRK1ACA12 | |
| SCHEMBL206103 | 0.75 | SMN1; SMN2 (0.41) | HTTGAADYRK1AAPPKDM4E | |
| SCHEMBL4718799 | 0.75 | SMN1; SMN2 (0.44) | HTTGAADYRK1ACA1CA2 | |
| SCHEMBL212513 | 0.75 | MAPT (0.44) | GAAL3MBTL1DYRK1AAPPKDM4E | |
| SCHEMBL206753 | 0.75 | GFER (0.44) | HTTDYRK1AAPPKDM4EALDH1A1 | |
| SCHEMBL207174 | 0.75 | HTT (0.38) | HTTDYRK1AAPPALDH1A1MAPT | |
| SCHEMBL7258260 | 0.75 | RAB9A (0.54) | HTTGAAL3MBTL1CA12CA1 | |
| SCHEMBL20542591 | 0.74 | — | — | |
| SCHEMBL5535847 | 0.72 | PIK3CA (0.50) | GAAL3MBTL1DYRK1AALDH1A1 | |
| SCHEMBL972859 | 0.71 | KDM4E (0.46) | HTTGAACA2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397488-A1 | NOVEL COMPOUNDS FOR CHEMILUMINESCENSE PROCEDURES | Roche Diagnostics GmbH (DE) | 2004-03-17 | — | — | EP | disclosed |
| WO-2002099097-A1 | NOVEL COMPOUNDS FOR CHEMILUMINESCENSE PROCEDURES | ROCHE DIAGNOSTICS GMBH (DE) | 2002-12-12 | — | — | WO | disclosed |
| US-4609438-A | ELECTROLYTIC, FROM A 2-MERCAPTOBENZOTHIAZOLE AND A BENZENESULFINATE | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1986-09-02 | — | — | US | disclosed |