Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 8/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3014917 | 1.00 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 | |
| Bromide SCHEMBL129468 | 1.00 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 | |
| Bromide SCHEMBL7761001 | 1.00 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 | |
| Bromide SCHEMBL130779 | 1.00 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 | |
| Bromide SCHEMBL21293895 | 1.00 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 | |
| Bromide SCHEMBL9465223 | 1.00 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 | |
| Bromide SCHEMBL21250203 | 1.00 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 | |
| Bromide SCHEMBL21293896 | 1.00 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 | |
| Bromide SCHEMBL21247774 | 1.00 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 | |
| Bromide SCHEMBL238107 | 1.00 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019155968-A1 | HAIR TREATMENT COMPOSITION | 株式会社資生堂 | 2019-08-15 | — | — | WO | disclosed |
| CN-105814092-B | Composition for hydrophilic cured product | 三井化学株式会社 | 2018-09-21 | — | — | CN | disclosed |
| CN-107430213-A | Hydrophilic optical feature monofilm and its layered product | 三井化学株式会社 | 2017-12-01 | — | — | CN | disclosed |
| CN-107250226-A | Acrylic resin modified solidfied material and its layered product and their manufacture method | 三井化学株式会社 | 2017-10-13 | — | — | CN | disclosed |
| CN-105814092-A | Composition for hydrophilic cured product | 三井化学株式会社 | 2016-07-27 | — | — | CN | disclosed |