Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 8/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3014917 | 1.00 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 | |
| Bromide SCHEMBL129468 | 1.00 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 | |
| Bromide SCHEMBL7761001 | 1.00 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 | |
| Bromide SCHEMBL21253124 | 1.00 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 | |
| Bromide SCHEMBL21293895 | 1.00 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 | |
| Bromide SCHEMBL9465223 | 1.00 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 | |
| Bromide SCHEMBL21250203 | 1.00 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 | |
| Bromide SCHEMBL21293896 | 1.00 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 | |
| Bromide SCHEMBL21247774 | 1.00 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 | |
| Bromide SCHEMBL238107 | 1.00 | DNM1 (1.00) | DNM1TSHRALDH1A1THRBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260055056-A1 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | WILLIAM M YARBROUGH FOUND (US) | 2026-02-26 | — | — | US | claimed |
| US-12310939-B2 | Method for treating rheumatoid arthritis | THE WILLIAM YARBROUGH FOUNDATION (US) | 2025-05-27 | — | — | US | claimed |
| US-20250161258-A1 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | THE WILLIAM M YARBROUGH FOUND (US) | 2025-05-22 | — | — | US | claimed |
| CN-120005681-A | Silicon carbide substrate cleaning agent and preparation method and application thereof | 广东麒瑞新材料科技有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-119842359-A | High-stability multi-component hybrid structural adhesive for new energy lithium battery and preparation method thereof | 博森新材料(烟台)有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-119776897-A | Preparation method and application of unsupported catalyst electrode | 北京化工大学 | 2025-04-08 | — | — | CN | claimed |
| CN-119680577-A | Preparation method of zinc-based composite piezoelectric catalyst and application of zinc-based composite piezoelectric catalyst in piezoelectric catalytic hydrogen production | 浙江精工集成科技股份有限公司 | 2025-03-25 | — | — | CN | claimed |
| US-12239626-B2 | Method for treating infectious diseases with isothiocyanate functional compounds | THE WILLIAM YARBROUGH FOUNDATION (US) | 2025-03-04 | — | — | US | claimed |
| CN-119331295-A | Extinction liquid for lens shading sheet, extinction lens shading sheet, preparation method and application of extinction liquid | 拓烯科技(衢州)有限公司 | 2025-01-21 | — | — | CN | claimed |
| CN-119264808-A | Composition, ionic gel coating, preparation method and application thereof | 清华大学 | 2025-01-07 | — | — | CN | claimed |
| WO-2005032521-A2 | NON-FLAMMABLE TOPICAL ANESTHETIC LIQUID AEROSOLS | COLLEGIUM PHARMACEUTICAL, INC. (US) | 2005-04-14 | — | — | WO | claimed |
| US-6838419-B2 | Mixtures of quaternary compounds | CRODA, INC. (US) | 2005-01-04 | — | — | US | claimed |
| US-20040167057-A1 | Mixtures of quaternary compounds | CRODA, INC. | 2004-08-26 | — | — | US | claimed |
| US-6514862-B2 | Particles, solvent and a quaternary ammonium compound such as (2-hydroxyethyl)trimethylammonium chloride; improved removal selectivity between a layer to be polished and a silicon nitride stop layer | SAMSUNG ELECTRONICS CO. LTD. (KR) | 2003-02-04 | — | — | US | claimed |
| US-20020064955-A1 | Wafer polishing slurry and chemical mechanical polishing (CMP) method using the same | CONVERSANT INTELLECTUAL PROPERTY MANAGEMENT INC. (CA) | 2002-05-30 | — | — | US | claimed |
| US-6283336-B1 | Article for the delivery of foam products | THE PROCTER & GAMBLE COMPANY | 2001-09-04 | — | — | US | claimed |
| US-5580422-A | INCLUSION OF A QUATERNARY COMPOUND PRODUCES A FIBER WITH HIGHER PULP STRENGTH | HOECHST CELANESE CORPORATION (US) | 1996-12-03 | — | — | US | claimed |
| US-5356748-A | Nonaqueous solvent containing dispersed resin grains and graft polymer stabilizer | FUJI PHOTO FILM CO., LTD. (JP) | 1994-10-18 | — | — | US | claimed |
| US-4429457-A | Process for manufacturing a printed circuit board | TOPPAN PRINTING CO., LTD. (JP) | 1984-02-07 | — | — | US | claimed |
| US-4105545-A | PROCESS FOR REMOVING CYANIDE-CONTAINING COMPONENTS FROM AQUEOUS MEDIA | TREADWELL CORP. (US) | 1978-08-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260055056-A1 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | ALK, C9, MSR1 | SIGMAR1 449/4885DNM1 4860/4885TSHR 1094/4885 |
| US-12239626-B2 | Method for treating infectious diseases with isothiocyanate functional compounds | CFTR, TST, ICMT | SIGMAR1 1678/4885DNM1 3945/4885TSHR 1685/4885 |
| US-12310939-B2 | Method for treating rheumatoid arthritis | MIF, TNF, MMP12 | SIGMAR1 1339/4885DNM1 3267/4885TSHR 1301/4885 |
| US-20250161258-A1 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | TST, TMSB10, NHERF1 | SIGMAR1 1720/4885DNM1 3740/4885TSHR 4015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.