Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 10/20 | 0.66 |
| ▸ | PRKCI | P41743 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MPI | P34949 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13837694 | 0.85 | PRKCZ (0.69) | PRKCZPRKCIALDH1A1HSD17B10HPGD | |
| SCHEMBL21248147 | 0.82 | POLB (0.51) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL3384989 | 0.82 | PRKCZ (0.74) | PRKCZPRKCIALDH1A1HSD17B10HPGD | |
| SCHEMBL8289654 | 0.80 | PRKCZ (1.00) | PRKCZPRKCIALDH1A1HSD17B10HPGD | |
| SCHEMBL690278 | 0.80 | PRKCZ (0.84) | PRKCZPRKCIALDH1A1HSD17B10HPGD | |
| SCHEMBL8290826 | 0.80 | PRKCZ (0.79) | PRKCZPRKCIALDH1A1HSD17B10HPGD | |
| SCHEMBL1554707 | 0.80 | PRKCZ (0.75) | PRKCZPRKCIALDH1A1HSD17B10HPGD | |
| SCHEMBL8290363 | 0.79 | PRKCZ (0.82) | PRKCZPRKCIALDH1A1HSD17B10HPGD | |
| SCHEMBL1554182 | 0.79 | PRKCZ (0.82) | PRKCZPRKCIALDH1A1HSD17B10HPGD | |
| SCHEMBL25487711 | 0.79 | PRKCZ (0.73) | PRKCZPRKCIALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3749650-A1 | NON-FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO Pharma (FR) | 2020-12-16 | — | — | EP | disclosed |
| CN-111936471-A | Non-fused thiophene derivative and use thereof | 埃尼奥制药公司 | 2020-11-13 | — | — | CN | disclosed |
| WO-2019154956-A1 | NON-FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2019-08-15 | — | — | WO | disclosed |