Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 7/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | PTPRC | P08575 | 1/20 | 0.50 |
| ▸ | PTPRF | P10586 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | PTPA | Q15257 | 1/20 | 0.50 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21248149 | 0.86 | HPGD (0.62) | POLBRAB9ALMNAPTPN1PTPRC | |
| SCHEMBL21253180 | 0.82 | PRKCZ (0.66) | RAB9AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4013374 | 0.75 | GSTO1 (0.59) | POLBRAB9ALMNAPTPN1PTPRC | |
| SCHEMBL4010031 | 0.73 | ALDH1A1 (0.57) | POLBRAB9ALMNAPTPN1PTPRC | |
| SCHEMBL23599197 | 0.72 | LMNA (0.74) | POLBRAB9ALMNAPTPN1PTPRC | |
| SCHEMBL21259033 | 0.72 | MAPK8 (0.46) | POLBLMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL21247938 | 0.72 | MAPK8 (0.47) | POLBRAB9ALMNAGSTO1ALDH1A1 | |
| SCHEMBL23580345 | 0.72 | LMNA (0.73) | POLBRAB9ALMNAPTPN1PTPRC | |
| SCHEMBL21247388 | 0.70 | MEN1 (0.58) | POLBRAB9ALMNAALDH1A1MAPT | |
| SCHEMBL11634946 | 0.70 | LMNA (0.74) | POLBRAB9ALMNAPTPN1PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3749650-A1 | NON-FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO Pharma (FR) | 2020-12-16 | — | — | EP | disclosed |
| WO-2019154956-A1 | NON-FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2019-08-15 | — | — | WO | disclosed |