Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 7/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | ADAM8 | P78325 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | NPY4R | P50391 | 3/20 | 0.33 |
| ▸ | NPY1R | P25929 | 2/20 | 0.33 |
| ▸ | NPY2R | P49146 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22873329 | 0.90 | SIRT2 (0.39) | FURINHTTSMN1; SMN2SIRT1MAP1LC3B | |
| SCHEMBL24728301 | 0.88 | FURIN (0.42) | FURINHTTSMN1; SMN2LMNAPOLB | |
| SCHEMBL20206643 | 0.88 | FURIN (0.42) | FURINHTTSMN1; SMN2LMNAPOLB | |
| SCHEMBL14234316 | 0.88 | FURIN (0.42) | FURINHTTSMN1; SMN2LMNAPOLB | |
| SCHEMBL20029727 | 0.85 | FURIN (0.35) | FURINHTTLMNAPOLBKMT2A | |
| SCHEMBL18244334 | 0.85 | FAP (0.40) | FURINHTTSMN1; SMN2MAP1LC3BNPY4R | |
| SCHEMBL18244335 | 0.85 | FAP (0.40) | FURINHTTSMN1; SMN2MAP1LC3BNPY4R | |
| SCHEMBL21965275 | 0.85 | FURIN (0.41) | FURINHTTSMN1; SMN2SIRT1 | |
| SCHEMBL21122921 | 0.85 | FURIN (0.41) | FURINHTTSMN1; SMN2LMNAPOLB | |
| SCHEMBL17133811 | 0.85 | FURIN (0.45) | FURINHTTSMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524273-A1 | CYSTEINE MODIFIED ANTIBODY-DRUG CONJUGATE AND PREPARATION METHOD THEREOF | Sichuan Baili Pharm Co., Ltd. (CN) | 2019-08-14 | — | — | EP | disclosed |