Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.39 |
| ▸ | FURIN | P09958 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21254306 | 0.90 | FURIN (0.38) | SIRT1FURINHTTMAP1LC3BSMN1; SMN2 | |
| SCHEMBL25765345 | 0.89 | SIRT2 (0.42) | SIRT2SIRT1SIRT3SIRT5FURIN | |
| SCHEMBL22067810 | 0.88 | FAP (0.39) | SIRT2SIRT1SIRT3SIRT5FURIN | |
| SCHEMBL21841772 | 0.86 | FURIN (0.39) | SIRT2SIRT1SIRT3SIRT5FURIN | |
| SCHEMBL23420151 | 0.84 | FAP (0.48) | SIRT2SIRT1SIRT3SIRT5MAP1LC3B | |
| SCHEMBL14978945 | 0.84 | FAP (0.48) | SIRT2SIRT1SIRT3SIRT5MAP1LC3B | |
| SCHEMBL27249189 | 0.84 | FAP (0.48) | SIRT2SIRT1SIRT3SIRT5MAP1LC3B | |
| SCHEMBL23843840 | 0.84 | FAP (0.48) | SIRT2SIRT1SIRT3SIRT5MAP1LC3B | |
| SCHEMBL24094770 | 0.83 | SIRT2 (0.44) | SIRT2SIRT1SIRT3SIRT5HTT | |
| SCHEMBL22479752 | 0.83 | SIRT1 (0.47) | SIRT2SIRT1SIRT3SIRT5FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3760233-B1 | ONE-POT PREPARATION PROCESS FOR ANTIBODY DRUG CONJUGATE INTERMEDIATE | MABPLEX INT CO LTD (CN) | 2023-07-12 | — | — | EP | disclosed |
| EP-3760233-A1 | ONE-POT PREPARATION PROCESS FOR ANTIBODY DRUG CONJUGATE INTERMEDIATE | Mabplex International, Ltd. (CN) | 2021-01-06 | — | — | EP | disclosed |