Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 5/20 | 0.35 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 3/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 2/20 | 0.32 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | ADAM8 | P78325 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPY4R | P50391 | 4/20 | 0.31 |
| ▸ | NPY1R | P25929 | 3/20 | 0.31 |
| ▸ | NPY2R | P49146 | 3/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21254306 | 0.85 | FURIN (0.38) | FURINMMP9ADAM10MMP2MMP12 | |
| SCHEMBL21898136 | 0.85 | FURIN (0.36) | FURINC3AR1MMP9MMP1MMP3 | |
| SCHEMBL20795891 | 0.84 | FURIN (0.36) | FURINC3AR1MMP9MMP1MMP3 | |
| SCHEMBL20159819 | 0.84 | FURIN (0.36) | FURINC3AR1MMP9MMP1MMP3 | |
| SCHEMBL23736705 | 0.84 | FURIN (0.36) | FURINC3AR1MMP9MMP1MMP3 | |
| SCHEMBL22873329 | 0.82 | SIRT2 (0.39) | FURINHTT | |
| SCHEMBL21503872 | 0.82 | FURIN (0.34) | FURIN | |
| SCHEMBL23395778 | 0.80 | ADAM10 (0.39) | FURINC3AR1MMP9ADAM10MMP2 | |
| SCHEMBL19619238 | 0.80 | FAP (0.40) | FURINNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL23236822 | 0.80 | BMP1 (0.36) | FURINC3AR1MMP9MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180094075-A1 | ANTI-PTK7 ANTIBODY-DRUG CONJUGATES | PFIZER INC. (US) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180094075-A1 | ANTI-PTK7 ANTIBODY-DRUG CONJUGATES | PTK2, PTK6, PTK2B | FURIN 1826/4885C3AR1 2456/4885MMP9 2931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.