Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.30 |
| ▸ | NOS2 | P35228 | 3/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29846963 | 0.72 | NOS3 (0.31) | NOS3NOS2NOS1 | |
| SCHEMBL17837498 | 0.72 | NOS3 (0.31) | NOS3NOS2NOS1 | |
| SCHEMBL22876719 | 0.71 | — | — | |
| SCHEMBL18625352 | 0.71 | NOS3 (0.30) | NOS3NOS2NOS1 | |
| SCHEMBL29856304 | 0.71 | NOS2 (0.34) | NOS3NOS2NOS1 | |
| SCHEMBL17857743 | 0.71 | NOS3 (0.30) | NOS3NOS2NOS1 | |
| SCHEMBL29552440 | 0.68 | TLR7 (0.31) | — | |
| SCHEMBL21307343 | 0.67 | — | — | |
| SCHEMBL2877700 | 0.66 | — | — | |
| SCHEMBL5679719 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233829-B1 | PYRIMIDINE AND TRIAZINE DERIVATIVES AND THEIR USE AS AXL INHIBITORS | PFIZER (US) | 2019-08-14 | — | — | EP | disclosed |