SCHEMBL21255720

SCHEMBL21255720

C1=NCCc2ccsc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15935593 0.77
SCHEMBL3826710 0.64
SCHEMBL739623 0.62
SCHEMBL6438498 0.61
SCHEMBL15871033 0.61 PNMT (0.33)
SCHEMBL741045 0.61
SCHEMBL19471742 0.61
SCHEMBL11861754 0.59 TRPA1 (0.55)
SCHEMBL3307465 0.58 NOS2 (0.61)
SCHEMBL8057615 0.58 NOS2 (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3752492-B1 FUNGICIDAL OXADIAZOLES BAYER AG (DE) 2022-12-21 EP disclosed
US-20210009541-A1 FUNGICIDAL OXADIAZOLES BAYER AKTIENGESELLSCHAFT (DE) 2021-01-14 US disclosed
WO-2020254493-A1 THIENYLHYDROXYISOXAZOLINES AND DERIVATIVES THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2020-12-24 WO disclosed
WO-2020254488-A1 HYDROXYISOXAZOLINES AND USE THEREOF AS FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 2020-12-24 WO disclosed
WO-2019155066-A1 FUNGICIDAL OXADIAZOLES BAYER AKTIENGESELLSCHAFT (DE) 2019-08-15 WO disclosed