Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.53 |
| ▸ | TOP1 | P11387 | 3/20 | 0.48 |
| ▸ | CYCS | P99999 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16912677 | 0.90 | TOP1 (0.54) | JAK3TOP1CYCSKDM4EALDH1A1 | |
| SCHEMBL8865129 | 0.81 | KMT2A (0.55) | TOP1CYCSKDM4EALDH1A1HPGD | |
| SCHEMBL8184067 | 0.78 | STAT3 (0.47) | JAK3TOP1KDM4EALDH1A1MMP2 | |
| SCHEMBL8184071 | 0.78 | STAT3 (0.47) | JAK3KDM4EALDH1A1MMP2MMP9 | |
| SCHEMBL16923748 | 0.78 | ALDH1A1 (0.55) | TOP1CYCSKDM4EALDH1A1HPGD | |
| SCHEMBL8572426 | 0.77 | TOP1 (0.53) | TOP1CYCSMEN1MAPTKMT2A | |
| SCHEMBL18917438 | 0.75 | TOP1 (0.69) | TOP1CYCSKDM4EALDH1A1HPGD | |
| SCHEMBL31121522 | 0.75 | TOP1 (0.62) | TOP1CYCSSTAT3STAT1 | |
| SCHEMBL31121523 | 0.75 | TOP1 (0.62) | TOP1CYCSSTAT3STAT1 | |
| SCHEMBL16920374 | 0.75 | SMN1; SMN2 (0.54) | TOP1CYCSKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1416970-B1 | CONJUGATE | PHOTOBIOTICS LTD (GB) | 2012-04-25 | — | — | EP | disclosed |
| US-7655753-B2 | Conjugate | PHOTOBIOTICS LIMITED (GB) | 2010-02-02 | — | — | US | disclosed |
| US-20050234222-A1 | Conjugate | PHOTOBIOTICS LIMITED (GB) | 2005-10-20 | — | — | US | disclosed |
| EP-1416970-A2 | CONJUGATE | Photobiotics Ltd. (GB) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003015825-A2 | CONJUGATE | PHOTOBIOTICS LTD (GB) | 2003-02-27 | — | — | WO | disclosed |