Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | MMP2 | P08253 | 6/20 | 0.41 |
| ▸ | MMP9 | P14780 | 6/20 | 0.41 |
| ▸ | MMP8 | P22894 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8184071 | 0.94 | STAT3 (0.47) | STAT3STAT1KDM4EMMP2MMP9 | |
| SCHEMBL2125691 | 0.78 | JAK3 (0.53) | STAT3STAT1KDM4EMMP2MMP9 | |
| SCHEMBL226835 | 0.73 | STAT3 (0.83) | STAT3STAT1TOP1 | |
| SCHEMBL29585686 | 0.73 | STAT3 (0.83) | STAT3STAT1TOP1 | |
| SCHEMBL8865129 | 0.73 | KMT2A (0.55) | STAT1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3107248 | 0.72 | STAT3 (0.64) | STAT3STAT1MAPTGAAAURKA | |
| SCHEMBL584789 | 0.71 | STAT3 (0.67) | STAT3STAT1MAPTGAAAURKA | |
| SCHEMBL455573 | 0.71 | STAT3 (0.67) | STAT3STAT1KDM4EALDH1A1HPGD | |
| SCHEMBL8186744 | 0.70 | STAT3 (0.55) | STAT3STAT1MMP2MMP9MMP8 | |
| SCHEMBL585272 | 0.70 | STAT3 (0.55) | STAT3STAT1HDAC1AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6087493-A | ENZYME IHIBITORS | REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-07-11 | — | — | US | claimed |