Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LCAT | P04180 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 2/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20148593 | 0.80 | OGA (0.62) | OGACHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL20857050 | 0.77 | TRPV6 (0.38) | CHRNB2CHRNA4CHRNB4CHRNA3MLLT1 | |
| SCHEMBL23126233 | 0.76 | OGA (0.57) | OGACHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL6884588 | 0.75 | CHRNB2 (0.61) | OGACHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL19627322 | 0.75 | CHRNB2 (0.51) | OGACHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL2353510 | 0.74 | ALDH1A1 (0.47) | MAPTSMN1; SMN2KCNH2 | |
| SCHEMBL5312452 | 0.74 | CHRNB2 (0.72) | OGACHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL1359572 | 0.73 | CHRNB2 (0.58) | OGACHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL8931633 | 0.73 | CHRNB2 (0.58) | OGACHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL4020437 | 0.73 | ALDH1A1 (0.46) | CHRNB2CHRNA4SMN1; SMN2KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443091-A1 | ANTHELMINTIC AGENTS AND THEIR USE | Intervet International B.V. (NL) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010146083-A1 | ANTHELMINTIC AGENTS AND THEIR USE | INTERVET INTERNATIONAL B.V. (NL) | 2010-12-23 | — | — | WO | disclosed |