Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 4/20 | 0.60 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.60 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.60 |
| ▸ | RNASEL | Q05823 | 2/20 | 0.58 |
| ▸ | P2RY1 | P47900 | 6/20 | 0.57 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.57 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.57 |
| ▸ | SRC | P12931 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.54 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.54 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.54 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24081997 | 0.89 | P2RX3 (0.57) | P2RX1P2RX3P2RX2RNASELP2RY1 | |
| SCHEMBL23761046 | 0.89 | P2RX3 (0.57) | P2RX1P2RX3P2RX2RNASELP2RY1 | |
| SCHEMBL20434903 | 0.88 | AHCY (0.54) | RNASELP2RY1P2RY2SRCSMN1; SMN2 | |
| SCHEMBL19503942 | 0.84 | P2RY1 (0.67) | P2RX1P2RX3P2RY1P2RX4P2RY11 | |
| SCHEMBL23760924 | 0.83 | ADCY5 (0.60) | P2RX1P2RX3P2RX2RNASELP2RY1 | |
| SCHEMBL19503941 | 0.83 | P2RY1 (0.68) | P2RX1P2RX3P2RY1P2RX4P2RY11 | |
| SCHEMBL77641 | 0.82 | POLB (0.81) | P2RX1P2RX3P2RX2RNASELP2RY1 | |
| SCHEMBL22498804 | 0.82 | P2RX1 (0.68) | P2RX1P2RX3P2RX2RNASELP2RY1 | |
| SCHEMBL2508784 | 0.82 | POLB (0.81) | P2RX1P2RX3P2RX2RNASELP2RY1 | |
| SCHEMBL7745739 | 0.82 | P2RX1 (0.68) | P2RX1P2RX3P2RX2RNASELP2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019157317-A1 | COMPOUNDS AND METHODS FOR TREATING ADDICTION AND RELATED DISORDERS | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2019-08-15 | — | — | WO | disclosed |