Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.73 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.61 |
| ▸ | PTPRC | P08575 | 1/20 | 0.61 |
| ▸ | PTPRF | P10586 | 1/20 | 0.61 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.61 |
| ▸ | PTPA | Q15257 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | ANO1 | Q5XXA6 | 4/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12314193 | 0.94 | MEN1 (0.79) | MEN1KMT2ANPC1GRIN2CRAB9A | |
| SCHEMBL15503705 | 0.92 | MEN1 (0.68) | MEN1KMT2ANPC1RAB9APTPN1 | |
| SCHEMBL13901723 | 0.86 | PTPN1 (0.80) | MEN1KMT2ARAB9APTPN1PTPRC | |
| SCHEMBL14803202 | 0.83 | MEN1 (0.58) | MEN1KMT2ANPC1GRIN2CRAB9A | |
| SCHEMBL21247164 | 0.82 | MEN1 (0.82) | MEN1KMT2ANPC1GRIN2CRAB9A | |
| SCHEMBL12314191 | 0.82 | MEN1 (1.00) | MEN1KMT2ANPC1GRIN2CRAB9A | |
| SCHEMBL14803701 | 0.81 | ANO1 (0.71) | MEN1KMT2AANO1 | |
| SCHEMBL21259152 | 0.79 | MEN1 (0.80) | MEN1KMT2ANPC1GRIN2CRAB9A | |
| SCHEMBL13926188 | 0.79 | MEN1 (0.88) | MEN1KMT2AANO1 | |
| SCHEMBL3628774 | 0.79 | CASP3 (0.83) | MEN1KMT2ANPC1GRIN2CRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11840527-B2 | Non-fused thiophene derivatives and their uses | ENYO PHARMA (FR) | 2023-12-12 | — | — | US | disclosed |
| US-11840527-B2 | Non-fused thiophene derivatives and their uses | ENYO PHARMA (FR) | 2023-12-12 | — | — | US | disclosed |
| US-20200369655-A1 | NON-FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2020-11-26 | — | — | US | disclosed |
| WO-2019154953-A1 | NON-FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2019-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369655-A1 | NON-FUSED THIOPHENE DERIVATIVES AND THEIR USES | FTH1, SLC40A1, FECH | MEN1 3578/4885KMT2A 3273/4885NPC1 320/4885 |
| US-11840527-B2 | Non-fused thiophene derivatives and their uses | FTH1, SLC40A1, FECH | MEN1 3578/4885KMT2A 3273/4885NPC1 320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.