Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.43 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.40 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038035 | 0.82 | ALDH1A1 (0.43) | LMNAALDH1A1MAPTMAPK1PRKCA | |
| Tributyrin SCHEMBL23825 | 0.81 | ALDH1A1 (0.72) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| Tributyrin SCHEMBL601928 | 0.81 | ALDH1A1 (0.72) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL13398485 | 0.81 | ALDH1A1 (0.87) | LMNAALDH1A1MAPTMAPK1PRKCA | |
| SCHEMBL15369110 | 0.81 | ALDH1A1 (0.87) | LMNAALDH1A1MAPTMAPK1PRKCA | |
| Tributyrin SCHEMBL17593578 | 0.80 | ALDH1A1 (0.66) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL24444306 | 0.80 | ALDH1A1 (0.65) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL24485672 | 0.80 | LMNA (0.60) | LMNAALDH1A1MAPTMAPK1PRKCA | |
| Tributyrin SCHEMBL8206257 | 0.79 | ALDH1A1 (0.70) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL21289215 | 0.79 | ALDH1A1 (0.70) | LMNAALDH1A1PRKCAPRKCEPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190248785-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO., LTD. (JP) | 2019-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190248785-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | PREP, UNG, DPP4 | LMNA 1238/4885ALDH1A1 1564/4885MAPT 4568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.