Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2127365 | 0.94 | SIRT6 (0.39) | SIRT6MAPTHTTLMNAL3MBTL1 | |
| SCHEMBL2126718 | 0.91 | CCNC (0.40) | SIRT6MAPTHTTLMNATMEM97 | |
| SCHEMBL2126816 | 0.88 | SIRT6 (0.41) | SIRT6MAPTHTTLMNAALDH1A1 | |
| SCHEMBL2127785 | 0.85 | CCNC (0.40) | SIRT6MAPTHTTLMNATMEM97 | |
| SCHEMBL2126360 | 0.83 | SERPINE1 (0.45) | MAPTHTTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL15740364 | 0.83 | SIRT6 (0.41) | SIRT6MAPTHTTLMNATMEM97 | |
| SCHEMBL15740464 | 0.83 | SIRT6 (0.41) | SIRT6MAPTHTTLMNAL3MBTL1 | |
| SCHEMBL2124155 | 0.83 | SERPINE1 (0.37) | SIRT6HTTLMNATMEM97ALDH1A1 | |
| SCHEMBL15740352 | 0.83 | SIRT6 (0.41) | SIRT6MAPTHTTLMNAL3MBTL1 | |
| SCHEMBL2125848 | 0.83 | SERPINE1 (0.37) | SIRT6MAPTHTTLMNATMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443091-A1 | ANTHELMINTIC AGENTS AND THEIR USE | Intervet International B.V. (NL) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010146083-A1 | ANTHELMINTIC AGENTS AND THEIR USE | INTERVET INTERNATIONAL B.V. (NL) | 2010-12-23 | — | — | WO | disclosed |