Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2126718 | 0.93 | CCNC (0.40) | CCNCCDK8SIRT6HRH3TMEM97 | |
| SCHEMBL2127365 | 0.91 | SIRT6 (0.39) | SIRT6TMEM97MAPTMAPK1HTT | |
| SCHEMBL2127281 | 0.87 | SIRT6 (0.41) | CCNCCDK8SIRT6HRH3MAPT | |
| SCHEMBL2128389 | 0.86 | SERPINE1 (0.45) | HRH3MAPTHTTALDH1A1LMNA | |
| SCHEMBL2125553 | 0.85 | SERPINE1 (0.36) | SIRT6TMEM97MAPTMAPK1HTT | |
| SCHEMBL2126004 | 0.85 | SIRT6 (0.40) | SIRT6TMEM97MAPTMAPK1HTT | |
| SCHEMBL2127941 | 0.84 | MEN1 (0.39) | MAPTMAPK1CYP2C9CYP2C19SLC6A9 | |
| SCHEMBL2118016 | 0.81 | CCNC (0.42) | CCNCCDK8SIRT6HRH3TMEM97 | |
| SCHEMBL2617807 | 0.81 | CCNC (0.42) | CCNCCDK8SIRT6HRH3TMEM97 | |
| SCHEMBL2617870 | 0.81 | CCNC (0.42) | CCNCCDK8SIRT6HRH3TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443091-A1 | ANTHELMINTIC AGENTS AND THEIR USE | Intervet International B.V. (NL) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010146083-A1 | ANTHELMINTIC AGENTS AND THEIR USE | INTERVET INTERNATIONAL B.V. (NL) | 2010-12-23 | — | — | WO | disclosed |