SCHEMBL2126343

SCHEMBL2126343

O=c1c2ccccc2sc2c(O)ccc(F)c12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.51
MAOB P27338 1/20 0.51
MAPT P10636 6/20 0.46
POLB P06746 4/20 0.46
ALDH1A1 P00352 3/20 0.46
LMNA P02545 3/20 0.46
HCRTR1 O43613 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
GAA P10253 1/20 0.44
ESR2 Q92731 2/20 0.43
ESR1 P03372 1/20 0.43
KDM4E B2RXH2 1/20 0.41
MAPK1 P28482 1/20 0.40
RECQL P46063 1/20 0.40
BLM P54132 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
SAE1 Q9UBE0 1/20 0.40
UBA2 Q9UBT2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5218956 0.87 MAOA (0.57) MAOAMAOBMAPTPOLBALDH1A1
SCHEMBL8078642 0.83 MAPT (0.57) MAOAMAOBMAPTPOLBALDH1A1
SCHEMBL2762900 0.81 MAOA (0.51) MAOAMAOBMAPTPOLBALDH1A1
SCHEMBL1615170 0.81 MAOB (0.51) MAOAMAOBMAPTPOLBALDH1A1
SCHEMBL17589800 0.78 MAOA (0.48) MAOAMAOBMAPTPOLBALDH1A1
SCHEMBL25556876 0.78 MAPT (0.58) MAOAMAOBMAPTPOLBALDH1A1
SCHEMBL28312469 0.77 MAPT (0.55) MAOAMAOBMAPTPOLBALDH1A1
SCHEMBL6712751 0.76 MAPT (0.43) MAOAMAOBMAPTPOLBALDH1A1
SCHEMBL16736486 0.75 MAPT (0.56) MAOAMAOBMAPTPOLBALDH1A1
SCHEMBL8413396 0.75 MAOA (0.51) MAOAMAOBMAPTPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2604663-B1 Curable liquids and inkjet inks for food packaging applications AGFA GRAPHICS NV (BE) 2017-08-09 EP disclosed
EP-2604663-B1 Curable liquids and inkjet inks for food packaging applications AGFA GRAPHICS NV (BE) 2017-08-09 EP disclosed
US-9718971-B2 Curable liquids and inkjet inks for food packaging applications AGFA GRAPHICS NV (BE) 2017-08-01 US disclosed
US-9718971-B2 Curable liquids and inkjet inks for food packaging applications AGFA GRAPHICS NV (BE) 2017-08-01 US disclosed
US-9718971-B2 Curable liquids and inkjet inks for food packaging applications AGFA GRAPHICS NV (BE) 2017-08-01 US disclosed
EP-2684876-B1 Polymerizable thioxanthones AGFA GRAPHICS NV (BE) 2016-09-14 EP disclosed
EP-2444429-B1 LED CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2016-09-07 EP disclosed
EP-2444429-B1 LED CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2016-09-07 EP disclosed
CN-104039898-B Curable liquids and inkjet inks for food packaging applications 爱克发印艺公司 2016-07-06 CN disclosed
EP-2447259-B1 Polymerisable photoinitiators for LED curable compositions AGFA GRAPHICS NV (BE) 2016-03-16 EP disclosed
EP-2174939-A1 Pyranones useful as ATM inhibitors Kudos Pharmaceuticals Limited (GB) 2010-04-14 EP disclosed
EP-2174939-A1 Pyranones useful as ATM inhibitors Kudos Pharmaceuticals Limited (GB) 2010-04-14 EP disclosed
EP-1485377-B1 PYRANONES USEFUL AS ATM INHIBITORS KUDOS PHARM LTD (GB) 2009-12-09 EP disclosed
EP-1485377-B1 PYRANONES USEFUL AS ATM INHIBITORS KUDOS PHARM LTD (GB) 2009-12-09 EP disclosed
CN-100358891-C Pyranones useful as ATM inhibitors KUDOS PHARM LTD (GB) 2008-01-02 CN disclosed
US-7049313-B2 ATM inhibitors KUDOS PHARMACEUTICALS LTD. (GB) 2006-05-23 US disclosed
CN-1639154-A Pyranones useful as ATM inhibitors KUDOS PHARM LTD (GB) 2005-07-13 CN disclosed
EP-1485377-A1 PYRANONES USEFUL AS ATM INHIBITORS Kudos Pharmaceuticals Limited (GB) 2004-12-15 EP disclosed
US-20040002492-A1 Induce immunology response; anticancer agents KUDOS PHARMACEUTICALS LTD (GB) 2004-01-01 US disclosed
WO-2003070726-A1 PYRANONES USEFUL AS ATM INHIBITORS KUDOS PHARMACEUTICALS LTD (GB) 2003-08-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040002492-A1 Induce immunology response; anticancer agents MYD88, IFNG, HCCS MAOA 3718/4885MAOB 3092/4885MAPT 4832/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.