Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3164229 | 0.83 | ALDH1A1 (0.55) | MAPTALDH1A1POLBHCRTR1L3MBTL1 | |
| SCHEMBL8078642 | 0.81 | MAPT (0.57) | MAPTALDH1A1POLBHCRTR1L3MBTL1 | |
| SCHEMBL30161909 | 0.80 | MAPT (0.61) | MAPTALDH1A1POLBHCRTR1L3MBTL1 | |
| SCHEMBL2126343 | 0.77 | MAOA (0.51) | MAPTALDH1A1POLBHCRTR1L3MBTL1 | |
| SCHEMBL16736486 | 0.77 | MAPT (0.56) | MAPTALDH1A1POLBHCRTR1L3MBTL1 | |
| SCHEMBL5218956 | 0.76 | MAOA (0.57) | MAPTALDH1A1POLBHCRTR1L3MBTL1 | |
| SCHEMBL8103104 | 0.75 | MAPT (0.65) | MAPTALDH1A1POLBHCRTR1L3MBTL1 | |
| SCHEMBL28311473 | 0.75 | MAPT (0.52) | MAPTALDH1A1POLBHCRTR1L3MBTL1 | |
| SCHEMBL3159460 | 0.74 | MAOB (0.52) | MAPTALDH1A1POLBHCRTR1L3MBTL1 | |
| SCHEMBL10059336 | 0.74 | MAPT (0.58) | MAPTALDH1A1POLBHCRTR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110139852-A | Tricyclic heterocyclic derivatives and use thereof | 奥克兰联合服务有限公司 | 2019-08-16 | — | — | CN | disclosed |