SCHEMBL2126353

SCHEMBL2126353

CC1(C)c2cc(-c3ccccc3)ccc2-c2c1ccc1ccccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 3/20 0.37
ESR1 P03372 2/20 0.36
ESR2 Q92731 2/20 0.36
PDK2 Q15119 1/20 0.36
DNMT1 P26358 1/20 0.35
CYP1A1 P04798 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP1B1 Q16678 1/20 0.35
CA12 O43570 3/20 0.34
CA1 P00915 3/20 0.34
CA2 P00918 3/20 0.34
CA9 Q16790 3/20 0.34
PGR P06401 2/20 0.34
TDP2 O95551 1/20 0.34
MAPT P10636 2/20 0.33
RARA P10276 1/20 0.33
RARB P10826 1/20 0.33
RARG P13631 1/20 0.33
LPL P06858 1/20 0.33
LIPG Q9Y5X9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17151655 0.93 MEN1 (0.37) GPR84ESR1ESR2PDK2MAPT
SCHEMBL18878316 0.93 MEN1 (0.37) GPR84ESR1ESR2PDK2MAPT
SCHEMBL18878282 0.93 MEN1 (0.37) GPR84ESR1ESR2PDK2MAPT
SCHEMBL19152739 0.92 GPR84 (0.34) GPR84ESR1ESR2PDK2DNMT1
SCHEMBL24453363 0.91 MEN1 (0.41) CYP1A1CYP1B1MAPTKDM4EALDH1A1
SCHEMBL19152691 0.91 GPR84 (0.33) GPR84ESR1ESR2PDK2DNMT1
SCHEMBL20466645 0.91 GPR84 (0.33) GPR84ESR1ESR2PDK2DNMT1
SCHEMBL17932706 0.91 MEN1 (0.37) GPR84MAPTRARARARBRARG
SCHEMBL19271320 0.91 HPGD (0.37) PDK2CYP1A1CYP1B1MAPTKDM4E
SCHEMBL23097259 0.90 PDK2 (0.40) PDK2DNMT1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8241763-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2012-08-14 US disclosed
EP-2038370-B1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-04-25 EP disclosed
US-20090261717-A1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2009-10-22 US disclosed
EP-2038370-A1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2009-03-25 EP disclosed
WO-2008006449-A1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2008-01-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090261717-A1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, SLC26A3, SLCO4C1 GPR84 4159/4885ESR1 412/4885ESR2 528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.