Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8681103 | 0.87 | KDM4E (0.50) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL8681140 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL8679962 | 0.84 | KDM4E (0.45) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL20848050 | 0.84 | KDM4E (0.40) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL8881998 | 0.83 | KDM4E (0.46) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL8680331 | 0.82 | SMN1; SMN2 (0.45) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL361847 | 0.81 | KDM4E (0.50) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL30284405 | 0.81 | KDM4E (0.50) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL3824699 | 0.81 | PDK2 (0.42) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL2127858 | 0.81 | CYP1A2 (0.39) | ALDH1A1KDM4EHPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5628935-A | Photochromic spironaphthopyran compounds | VISION-EASE LENS, INC. (US) | 1997-05-13 | — | — | US | claimed |
| US-5395567-A | For use in ophthalmic lenses; efficient reversible color change on exposure to uv rad | PPG INDUSTRIES, INC. (US) | 1995-03-07 | — | — | US | claimed |
| US-20170218132-A1 | METHOD OF MAKING PLASTIC ARTICLE | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2017-08-03 | — | — | US | disclosed |
| US-20120218511-A1 | Production Of Optical Elements | HOYA OPTICAL LABS OF AMERICA, INC. | 2012-08-30 | — | — | US | disclosed |
| EP-1464479-B1 | Production of optical elements | INSIGHT EQUITY A P X LP (US) | 2012-04-25 | — | — | EP | disclosed |
| US-20110317125-A1 | Production Of Optical Elements | HOYA OPTICAL LABS OF AMERICA, INC. | 2011-12-29 | — | — | US | disclosed |
| US-8029705-B2 | Production of optical elements | INSIGHT EQUITY A.P.X., L.P. (US) | 2011-10-04 | — | — | US | disclosed |
| EP-0814956-B2 | PRODUCTION OF OPTICAL ELEMENTS | INSIGHT EQUITY A P X LP (US) | 2010-12-15 | — | — | EP | disclosed |
| US-20060182972-A1 | Production of optical elements | HOYA OPTICAL LABS OF AMERICA, INC. | 2006-08-17 | — | — | US | disclosed |
| US-7048997-B2 | Production of optical elements | VISION-EASE LENS (US) | 2006-05-23 | — | — | US | disclosed |
| US-6814896-B2 | Production of optical elements | VISION-EASE LENS, INC. | 2004-11-09 | — | — | US | disclosed |
| US-5856860-A | Multi-focal optical elements | VISION-EASE LENS, INC. (US) | 1999-01-05 | — | — | US | disclosed |
| EP-0814956-A4 | PRODUCTION OF OPTICAL ELEMENTS | BMC IND INC (US) | 1998-12-30 | — | — | EP | disclosed |
| US-5827614-A | LAMINATING FIRST THERMOPLASTIC RESIN SHEET AND FUNCTIONAL MEMBER, AFFIXING FIRST THERMOPLASTIC RESIN SHEET TO POWER PORTION OF OPTICAL ELEMENT; OPHTHALMIC LENSES; ABRASION RESISTANCE | VISION-EASE LENS, INC. (US) | 1998-10-27 | — | — | US | disclosed |
| US-5757459-A | Multifocal optical elements | VISION-EASE LENS, INC. (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0814956-A1 | PRODUCTION OF OPTICAL ELEMENTS | BMC INDUSTRIES, INC. (US) | 1998-01-07 | — | — | EP | disclosed |
| US-5705102-A | Photochromic spironaphthopyran compounds | VISION-EASE LENS, INC. (US) | 1998-01-06 | — | — | US | disclosed |
| US-5628935-A | Photochromic spironaphthopyran compounds | VISION-EASE LENS, INC. (US) | 1997-05-13 | — | — | US | disclosed |
| WO-1996027496-A1 | PRODUCTION OF OPTICAL ELEMENTS | BMC INDUSTRIES, INC. (US) | 1996-09-12 | — | — | WO | disclosed |
| US-5395567-A | For use in ophthalmic lenses; efficient reversible color change on exposure to uv rad | PPG INDUSTRIES, INC. (US) | 1995-03-07 | — | — | US | disclosed |