SCHEMBL8680331

SCHEMBL8680331

CN1c2ccccc2C2(C=Cc3c(ccc4ccccc34)O2)c2ccccc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.45
HTT P42858 5/20 0.45
MAPT P10636 12/20 0.43
KDM4E B2RXH2 9/20 0.43
MEN1 O00255 6/20 0.43
KMT2A Q03164 6/20 0.43
GAA P10253 6/20 0.43
ALDH1A1 P00352 6/20 0.43
LMNA P02545 5/20 0.43
HPGD P15428 4/20 0.43
NPC1 O15118 2/20 0.43
GLA P06280 2/20 0.43
THRB P10828 4/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
ALOX12 P18054 2/20 0.40
PKM P14618 2/20 0.40
MAPK1 P28482 2/20 0.38
CA12 O43570 1/20 0.37
CA9 Q16790 1/20 0.37
CBX7 O95931 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2126375 0.82 ALDH1A1 (0.54) SMN1; SMN2HTTMAPTKDM4EMEN1
SCHEMBL8681103 0.81 KDM4E (0.50) SMN1; SMN2HTTMAPTKDM4EMEN1
SCHEMBL8681140 0.80 ALDH1A1 (0.49) SMN1; SMN2HTTMAPTKDM4EMEN1
SCHEMBL8679962 0.78 KDM4E (0.45) SMN1; SMN2HTTMAPTKDM4EMEN1
SCHEMBL1323078 0.77 PRKDC (0.36) SMN1; SMN2HTTMAPTKDM4EMEN1
SCHEMBL29848328 0.76 MAPT (0.63) SMN1; SMN2HTTMAPTKDM4EMEN1
SCHEMBL29931020 0.76 MAPT (0.63) SMN1; SMN2HTTMAPTKDM4EMEN1
SCHEMBL1894170 0.76 MAPT (0.63) SMN1; SMN2HTTMAPTKDM4EMEN1
SCHEMBL30284405 0.76 KDM4E (0.50) SMN1; SMN2HTTMAPTKDM4EMEN1
SCHEMBL361847 0.76 KDM4E (0.50) SMN1; SMN2HTTMAPTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US claimed
US-5710420-A Method for embedding and recovering machine-readable information XEROX CORPORATION (US) 1998-01-20 US disclosed
US-5633109-A Ink compositions with liposomes containing photochromic compounds XEROX CORPORATION (US) 1997-05-27 US disclosed
US-5593486-A Photochromic hot melt ink compositions XEROX CORPORATION (US) 1997-01-14 US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 US disclosed