Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.82 |
| ▸ | MEN1 | O00255 | 4/20 | 0.82 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.82 |
| ▸ | DPP4 | P27487 | 1/20 | 0.82 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.82 |
| ▸ | RELA | Q04206 | 1/20 | 0.82 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.82 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.82 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.72 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.72 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.70 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Helichrysetin SCHEMBL30382622 | 1.00 | MAPT (0.82) | MAPTKMT2AMEN1NFKB1DPP4 | |
| Helichrysetin SCHEMBL2126372 | 1.00 | MAPT (0.82) | MAPTKMT2AMEN1NFKB1DPP4 | |
| Helichrysetin SCHEMBL30383770 | 0.99 | MAPT (0.80) | MAPTKMT2AMEN1NFKB1DPP4 | |
| SCHEMBL4834940 | 0.93 | TDP1 (0.83) | MAPTKMT2AMEN1NFKB1DPP4 | |
| SCHEMBL4834935 | 0.93 | TDP1 (0.83) | MAPTKMT2AMEN1NFKB1DPP4 | |
| SCHEMBL2286236 | 0.92 | ABCG2 (0.87) | MAPTKMT2AMEN1NFKB1DPP4 | |
| SCHEMBL30383859 | 0.92 | MAPT (0.78) | MAPTKMT2AMEN1NFKB1DPP4 | |
| SCHEMBL2286389 | 0.92 | MAPT (0.78) | MAPTKMT2AMEN1NFKB1DPP4 | |
| SCHEMBL2286384 | 0.92 | MAPT (0.78) | MAPTKMT2AMEN1NFKB1DPP4 | |
| SCHEMBL30383887 | 0.92 | ABCG2 (0.87) | MAPTKMT2AMEN1NFKB1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12343317-B2 | Compositions and methods for treating bleeding and bleeding disorders | YewSavin, Inc. (US) | 2025-07-01 | — | — | US | disclosed |
| CN-117321028-A | Method for synthesizing xanthohumol | 普罗克森有限责任公司 | 2023-12-29 | — | — | CN | disclosed |
| US-20230190679-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-06-22 | — | — | US | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |
| US-9061984-B2 | Compounds related to chalcones and benzothienopyrimidines, their synthesis, and uses to treat diseases | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2015-06-23 | — | — | US | disclosed |
| US-20120110703-A1 | PROTEIN HAVING NOVEL PRENYLTRANSFERASE ACTIVITY AND GENE ENCODING THE SAME | KIRIN HOLDINGS KABUSHIKI KAISHA (JP) | 2012-05-03 | — | — | US | disclosed |
| EP-2444493-A1 | PROTEIN HAVING NOVEL PRENYLATION ENZYME ACTIVITY AND GENE ENCODING SAME | Kirin Holdings Kabushiki Kaisha (JP) | 2012-04-25 | — | — | EP | disclosed |
| US-20110190325-A1 | COMPOUNDS, THEIR SYNTHESES, AND THIER USES | THE JOHNS HOPKINS UNIVERSITY | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230190679-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | SERPINC1, SERPINE1, SERPINH1 | MAPT 3512/4885KMT2A 3188/4885MEN1 2457/4885 |
| US-20110190325-A1 | COMPOUNDS, THEIR SYNTHESES, AND THIER USES | TERT, TYMS, NISCH | MAPT 2194/4885KMT2A 1587/4885MEN1 37/4885 |
| US-12343317-B2 | Compositions and methods for treating bleeding and bleeding disorders | SERPINC1, SERPINE1, SERPINH1 | MAPT 3512/4885KMT2A 3188/4885MEN1 2457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.