Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.82 |
| ▸ | MEN1 | O00255 | 4/20 | 0.82 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.82 |
| ▸ | DPP4 | P27487 | 1/20 | 0.82 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.82 |
| ▸ | RELA | Q04206 | 1/20 | 0.82 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.82 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.82 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.72 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.72 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.70 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Helichrysetin SCHEMBL2126376 | 1.00 | MAPT (0.82) | MAPTKMT2AMEN1NFKB1DPP4 | |
| Helichrysetin SCHEMBL30382622 | 1.00 | MAPT (0.82) | MAPTKMT2AMEN1NFKB1DPP4 | |
| Helichrysetin SCHEMBL30383770 | 0.99 | MAPT (0.80) | MAPTKMT2AMEN1NFKB1DPP4 | |
| SCHEMBL4834940 | 0.93 | TDP1 (0.83) | MAPTKMT2AMEN1NFKB1DPP4 | |
| SCHEMBL4834935 | 0.93 | TDP1 (0.83) | MAPTKMT2AMEN1NFKB1DPP4 | |
| SCHEMBL2286236 | 0.92 | ABCG2 (0.87) | MAPTKMT2AMEN1NFKB1DPP4 | |
| SCHEMBL30383859 | 0.92 | MAPT (0.78) | MAPTKMT2AMEN1NFKB1DPP4 | |
| SCHEMBL2286389 | 0.92 | MAPT (0.78) | MAPTKMT2AMEN1NFKB1DPP4 | |
| SCHEMBL2286384 | 0.92 | MAPT (0.78) | MAPTKMT2AMEN1NFKB1DPP4 | |
| SCHEMBL30383887 | 0.92 | ABCG2 (0.87) | MAPTKMT2AMEN1NFKB1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230338362-A1 | METHODS AND COMPOSITIONS FOR TREATING VIRAL INFECTIONS | IATERION, INC, | 2023-10-26 | — | — | US | claimed |
| EP-4213820-A1 | METHODS AND COMPOSITIONS FOR TREATING VIRAL INFECTIONS | Iaterion, Inc. (US) | 2023-07-26 | — | — | EP | claimed |
| WO-2022060822-A1 | METHODS AND COMPOSITIONS FOR TREATING VIRAL INFECTIONS | IATERION, INC. (US) | 2022-03-24 | — | — | WO | claimed |
| US-20260014100-A1 | Compositions and Methods for Treating Bleeding and Bleeding Disorders | YEWSAVIN INC (US) | 2026-01-15 | — | — | US | disclosed |
| US-12419856-B1 | Method of treating middle east respiratory syndrome (MERS) | KING SAUD UNIVERSITY (SA) | 2025-09-23 | — | — | US | disclosed |
| US-20250221944-A1 | COMPOSITION FOR PREVENTING OR TREATING MULTIPLE MYELOMA COMPRISING NOVEL CHROMANON COMPOUND AS ACTIVE INGREDIENT | KBLUEBIO INC (KR) | 2025-07-10 | — | — | US | disclosed |
| US-12343317-B2 | Compositions and methods for treating bleeding and bleeding disorders | YewSavin, Inc. (US) | 2025-07-01 | — | — | US | disclosed |
| CN-119837849-B | Application of helichrysin in preparation of drugs for relieving and treating cell erythroid differentiation disorder of subjects | 中国科学院北京基因组研究所(国家生物信息中心) | 2025-06-13 | — | — | CN | disclosed |
| CN-119837849-A | Application of helichrysin in preparation of drugs for relieving and treating cell erythroid differentiation disorder of subjects | 中国科学院北京基因组研究所(国家生物信息中心) | 2025-04-18 | — | — | CN | disclosed |
| EP-4506328-A1 | COMPOSITION FOR PREVENTING OR TREATING MULTIPLE MYELOMA COMPRISING NOVEL CHROMANON COMPOUND AS ACTIVE INGREDIENT | KBlueBio Inc (KR) | 2025-02-12 | — | — | EP | disclosed |
| US-12208082-B1 | Method of treating middle east respiratory syndrome (MERS) | KING SAUD UNIVERSITY (SA) | 2025-01-28 | — | — | US | disclosed |
| US-9061984-B2 | Compounds related to chalcones and benzothienopyrimidines, their synthesis, and uses to treat diseases | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2015-06-23 | — | — | US | disclosed |
| US-9061984-B2 | Compounds related to chalcones and benzothienopyrimidines, their synthesis, and uses to treat diseases | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2015-06-23 | — | — | US | disclosed |
| US-9061984-B2 | Compounds related to chalcones and benzothienopyrimidines, their synthesis, and uses to treat diseases | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2015-06-23 | — | — | US | disclosed |
| US-20120110703-A1 | PROTEIN HAVING NOVEL PRENYLTRANSFERASE ACTIVITY AND GENE ENCODING THE SAME | KIRIN HOLDINGS KABUSHIKI KAISHA (JP) | 2012-05-03 | — | — | US | disclosed |
| EP-2444493-A1 | PROTEIN HAVING NOVEL PRENYLATION ENZYME ACTIVITY AND GENE ENCODING SAME | Kirin Holdings Kabushiki Kaisha (JP) | 2012-04-25 | — | — | EP | disclosed |
| US-20110190325-A1 | COMPOUNDS, THEIR SYNTHESES, AND THIER USES | THE JOHNS HOPKINS UNIVERSITY | 2011-08-04 | — | — | US | disclosed |
| US-20110190325-A1 | COMPOUNDS, THEIR SYNTHESES, AND THIER USES | THE JOHNS HOPKINS UNIVERSITY | 2011-08-04 | — | — | US | disclosed |
| US-20110190325-A1 | COMPOUNDS, THEIR SYNTHESES, AND THIER USES | THE JOHNS HOPKINS UNIVERSITY | 2011-08-04 | — | — | US | disclosed |
| WO-2010019861-A1 | COMPOUNDS, THEIR SYNTHESES, AND THEIR USES | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2010-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230338362-A1 | METHODS AND COMPOSITIONS FOR TREATING VIRAL INFECTIONS | TREH, HAVCR2, CTRB1 | MAPT 1732/4885KMT2A 3827/4885MEN1 796/4885 |
| US-20260014100-A1 | Compositions and Methods for Treating Bleeding and Bleeding Disorders | SERPINC1, F2, F13B | MAPT 3297/4885KMT2A 2792/4885MEN1 3367/4885 |
| US-12419856-B1 | Method of treating middle east respiratory syndrome (MERS) | SARS1, CKMT1A; CKMT1B, CHCHD6 | MAPT 1401/4885KMT2A 2078/4885MEN1 1237/4885 |
| US-20110190325-A1 | COMPOUNDS, THEIR SYNTHESES, AND THIER USES | TERT, TYMS, NISCH | MAPT 2194/4885KMT2A 1587/4885MEN1 37/4885 |
| US-12343317-B2 | Compositions and methods for treating bleeding and bleeding disorders | SERPINC1, SERPINE1, SERPINH1 | MAPT 3512/4885KMT2A 3188/4885MEN1 2457/4885 |
| US-12208082-B1 | Method of treating middle east respiratory syndrome (MERS) | SARS1, CKMT1A; CKMT1B, CHCHD6 | MAPT 1401/4885KMT2A 2078/4885MEN1 1237/4885 |
| US-20250221944-A1 | COMPOSITION FOR PREVENTING OR TREATING MULTIPLE MYELOMA COMPRISING NOVEL CHROMANON COMPOUND AS ACTIVE INGREDIENT | MCL1, CRBN, BCL3 | MAPT 4100/4885KMT2A 1630/4885MEN1 338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.