Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.51 |
| ▸ | ACE | P12821 | 3/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14753735 | 0.89 | MMP8 (0.52) | MMP8ACEHSD17B10LMNAL3MBTL1 | |
| SCHEMBL21264079 | 0.82 | ACE (0.65) | ACETRPA1 | |
| SCHEMBL892960 | 0.82 | MMP8 (0.61) | MMP8HSD17B10LMNAL3MBTL1MAPT | |
| SCHEMBL8345051 | 0.81 | HSD17B10 (0.56) | MMP8HSD17B10LMNAL3MBTL1EPHX2 | |
| SCHEMBL14874554 | 0.81 | HSD17B10 (0.56) | MMP8HSD17B10LMNAL3MBTL1EPHX2 | |
| SCHEMBL10429976 | 0.81 | MMP8 (0.56) | MMP8ACETRPA1HSD17B10LMNA | |
| SCHEMBL27968398 | 0.81 | SMN1; SMN2 (0.53) | MMP8ACEHSD17B10LMNAL3MBTL1 | |
| SCHEMBL21264080 | 0.80 | ACE (0.50) | ACETRPA1 | |
| SCHEMBL5085947 | 0.80 | MMP8 (0.55) | MMP8ACETRPA1HSD17B10LMNA | |
| SCHEMBL14874590 | 0.79 | MMP8 (0.43) | MMP8ACEHSD17B10LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019154663-A1 | NEW PYRIDINE CARBOXAMIDES | BASF SE (DE) | 2019-08-15 | — | — | WO | disclosed |