SCHEMBL5085947

SCHEMBL5085947

CCOC(=O)C(Cc1ccccc1)C(C)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.55
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
NPC1 O15118 2/20 0.49
L3MBTL1 Q9Y468 3/20 0.48
LMNA P02545 2/20 0.48
PIN1 Q13526 1/20 0.46
TRPA1 O75762 1/20 0.46
ALDH1A1 P00352 2/20 0.46
EPHX2 P34913 1/20 0.46
PPARG P37231 1/20 0.46
TP53 P04637 1/20 0.46
METAP2 P50579 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
NPY1R P25929 1/20 0.45
NPY2R P49146 1/20 0.45
SLC1A3 P43003 1/20 0.45
SLC1A2 P43004 1/20 0.45
SLC1A1 P43005 1/20 0.45
RAB9A P51151 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL892960 0.90 MMP8 (0.61) MMP8MEN1KMT2ANPC1L3MBTL1
SCHEMBL10429976 0.88 MMP8 (0.56) MMP8MEN1KMT2ANPC1L3MBTL1
SCHEMBL5143568 0.87 MMP8 (0.55) MMP8MEN1KMT2ANPC1L3MBTL1
SCHEMBL13752142 0.85 MMP8 (0.54) MMP8MEN1KMT2ANPC1L3MBTL1
SCHEMBL5145270 0.85 MMP8 (0.54) MMP8MEN1KMT2ANPC1L3MBTL1
SCHEMBL7420068 0.85 MMP8 (0.54) MMP8MEN1KMT2ANPC1L3MBTL1
SCHEMBL3123872 0.85 MMP8 (0.54) MMP8MEN1KMT2ANPC1L3MBTL1
SCHEMBL7431774 0.85 KMT2A (0.62) MEN1KMT2ANPC1L3MBTL1ALDH1A1
SCHEMBL27622664 0.85 MMP8 (0.56) MMP8MEN1KMT2ANPC1L3MBTL1
SCHEMBL15016003 0.85 MMP8 (0.56) MMP8MEN1KMT2ANPC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200317674-A1 PYRAZOLOPYRIMIDINE DERIVATIVES AND THE COMPOSITIONS AND METHODS OF TREATMENT REGARDING THE SAME An2H Discovery Limited (IE) 2020-10-08 US disclosed
EP-1746110-B1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2015-03-11 EP disclosed
US-7351778-B2 Catalyst component for olefin polymerization and catalyst comprising the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-04-01 US disclosed
EP-1746110-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF China Petroleum & Chemical Corporation (CN) 2007-01-24 EP disclosed
US-20060287446-A1 Catalyst component for olefin polymerization and catalyst comprising the same BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CHINA PETROLEUM & CHEMICAL COPORATION (CN) 2006-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200317674-A1 PYRAZOLOPYRIMIDINE DERIVATIVES AND THE COMPOSITIONS AND METHODS OF TREATMENT REGARDING THE SAME PINK1, ADRM1, LRRK2 MMP8 2965/4885MEN1 4725/4885KMT2A 2432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.