Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | WNT1 | P04628 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608537 | 0.78 | THRB (0.61) | THRBTSHRHSD17B10ALDH1A1PKM | |
| SCHEMBL24568144 | 0.77 | RAB9A (0.42) | WNT1GSK3BDYRK1ATSHRALDH1A1 | |
| SCHEMBL24568358 | 0.74 | RAB9A (0.40) | WNT1GSK3BDYRK1A | |
| SCHEMBL20416291 | 0.73 | THRB (0.42) | THRBTSHRHSD17B10ALDH1A1PKM | |
| SCHEMBL25975362 | 0.73 | RAB9A (0.50) | THRBTSHRHSD17B10ALDH1A1PKM | |
| SCHEMBL17221436 | 0.73 | CYP4F2 (0.35) | TSHRHSD17B10 | |
| SCHEMBL23822907 | 0.71 | THRB (0.41) | THRBTSHRHSD17B10 | |
| SCHEMBL12858249 | 0.71 | RAB9A (0.53) | THRBTSHRHSD17B10ALDH1A1PKM | |
| SCHEMBL27402648 | 0.71 | THRB (0.41) | THRBTSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL26979715 | 0.71 | THRB (0.41) | THRBTSHRHSD17B10PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019157417-A1 | HETEROCYCLIC P2Y14 RECEPTOR ANTAGONISTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2019-08-15 | — | — | WO | disclosed |