Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12858249 | 0.97 | RAB9A (0.53) | RAB9ATSHRHSD17B10PKMSMN1; SMN2 | |
| SCHEMBL20103706 | 0.83 | THRB (0.39) | RAB9ATSHRHSD17B10PKMSMN1; SMN2 | |
| SCHEMBL20416291 | 0.79 | THRB (0.42) | RAB9ATSHRHSD17B10PKMSMN1; SMN2 | |
| SCHEMBL23822907 | 0.77 | THRB (0.41) | RAB9ATSHRHSD17B10THRB | |
| SCHEMBL27402648 | 0.77 | THRB (0.41) | RAB9ATSHRHSD17B10THRB | |
| SCHEMBL4449130 | 0.77 | THRB (0.37) | RAB9ATSHRHSD17B10PKMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL26979715 | 0.77 | THRB (0.41) | RAB9ATSHRHSD17B10PKMTHRB | |
| SCHEMBL5104779 | 0.75 | PKM (0.56) | RAB9ATSHRHSD17B10PKMSMN1; SMN2 | |
| SCHEMBL25783651 | 0.75 | PKM (0.50) | RAB9APKMTHRB | |
| SCHEMBL21264043 | 0.73 | THRB (0.39) | TSHRHSD17B10PKMALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050370-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | 1CBIO, INC. (US) | 2024-03-07 | — | — | WO | disclosed |
| WO-2023196429-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-10-12 | — | — | WO | disclosed |
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |