SCHEMBL21264582

SCHEMBL21264582

N#Cc1ccc2cc3n(-c4cccc([Si](c5ccccc5)(c5ccccc5)c5cccc(-n6c7ccccc7n7c8ccccc8cc67)c5)c4)c4ccccc4n3c2c1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 16/20 0.39
PLA2G10 O15496 1/20 0.36
PLA2G2A P14555 1/20 0.36
CDC7 O00311 1/20 0.34
CDK2 P24941 1/20 0.34
RPS6KB1 P23443 1/20 0.34
ACSS2 Q9NR19 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21264550 0.89 ACSS2 (0.36) TDP2PLA2G10PLA2G2ACDC7CDK2
SCHEMBL21264776 0.87 ALDH1A1 (0.38) PLA2G10
SCHEMBL21264831 0.86 ALDH1A1 (0.37) PLA2G10
SCHEMBL21264480 0.78 RPS6KB1 (0.38) TDP2PLA2G10PLA2G2ARPS6KB1ACSS2
SCHEMBL21264692 0.78 MAPK1 (0.33)
SCHEMBL21264830 0.77 ALDH1A1 (0.35) PLA2G10
SCHEMBL21264646 0.77 ALDH1A1 (0.40)
SCHEMBL21264551 0.76 CA1 (0.35) TDP2PLA2G10PLA2G2ACDC7CDK2
SCHEMBL21264787 0.74 ALDH1A1 (0.35) PLA2G10
SCHEMBL21264786 0.74 ALDH1A1 (0.39) PLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190252623-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2019-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190252623-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ZYX, NSD3, NES TDP2 4447/4885PLA2G10 3999/4885PLA2G2A 4356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.