⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1799780 | 0.85 | DGKA (0.39) | — | |
| SCHEMBL11269486 | 0.82 | ACHE (0.40) | — | |
| SCHEMBL10704254 | 0.81 | — | — | |
| SCHEMBL8979257 | 0.80 | — | — | |
| SCHEMBL8343153 | 0.79 | — | — | |
| Ethylene SCHEMBL3385945 | 0.78 | TSHR (0.48) | — | |
| SCHEMBL475320 | 0.77 | ADRA2A (0.52) | — | |
| SCHEMBL822230 | 0.77 | MGAM (0.48) | — | |
| SCHEMBL817110 | 0.77 | — | — | |
| SCHEMBL8188256 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015042170-A1 | COMPOSITIONS AND USES OF COMBINATIONS OF DIM-RELATED INDOLES AND SELECTED ANTI-ANDROGEN COMPOUNDS | WAYNE STATE UNIVERSITY (US) | 2015-03-26 | — | — | WO | claimed |
| US-20130034501-A1 | DIARYLHYDANTOIN COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-02-07 | — | — | US | claimed |
| EP-1893196-A4 | DIARYLHYDANTOIN COMPOUNDS | UNIV CALIFORNIA (US) | 2009-03-18 | — | — | EP | claimed |
| JP-2008540523-A | — | — | 2008-11-20 | — | — | JP | claimed |
| EP-1893196-A1 | DIARYLHYDANTOIN COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-03-05 | — | — | EP | claimed |
| US-20070004753-A1 | N-methyl-4-{4-[7-(4-cyano-3 -trifluoromethylphenyl)-6,8-dioxo-5,7-diazaspiro[3.4]oct-5-yl]-phenyl}butyramide; for treatment of hormone refractory prostate cancer | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-01-04 | — | — | US | claimed |
| WO-2006124118-A1 | DIARYLHYDANTOIN COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-11-23 | — | — | WO | claimed |
| US-3971740-A | DYES FOR POLYESTER FIBERS | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | claimed |
| US-20240132452-A1 | DIARYLHYDANTOIN COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-04-25 | — | — | US | disclosed |
| CN-116003328-A | Diaryl hydantoin compounds | 加利福尼亚大学董事会 | 2023-04-25 | — | — | CN | disclosed |
| US-20230109968-A1 | DIARYLHYDANTOIN COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-04-13 | — | — | US | disclosed |
| CN-110003114-B | Diarylhydantoin compounds | 加利福尼亚大学董事会 | 2023-01-17 | — | — | CN | disclosed |
| CN-113817152-B | Flame-retardant anti-dripping copolyester based on high-temperature self-crosslinking and preparation method and application thereof | 四川大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-113817152-A | Flame-retardant anti-dripping copolyester based on high-temperature self-crosslinking and preparation method and application thereof | 四川大学 | 2021-12-21 | — | — | CN | disclosed |
| US-5062861-A | NOVEL NAVY AND BLACK DISPERSE DYE MIXTURES INCLUDING AMINO-PHENYL THIOPHENE AZO DISPERSE DYE AND RED, YELLOW OR ORANGE DISPERSE DYES | BASF AKTIENGESELLSCHAFT (DE) | 1991-11-05 | — | — | US | disclosed |
| EP-0392359-A1 | Marine blue and black dyestuff mixtures | BASF Aktiengesellschaft (DE) | 1990-10-17 | — | — | EP | disclosed |
| US-4398913-A | ALKALINE PASTES | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4252604-A | OPTICAL BRIGHTENERS | SANDOZ LTD. (CH) | 1981-02-24 | — | — | US | disclosed |
| US-4086208-A | Flame resistant polyesters | TOYO BOSEKI KABUSHIKI KAISHA (JA) | 1978-04-25 | — | — | US | disclosed |
| US-4026931-A | AZO DYES, FIBER-REACTIVE; INDOLE OR 5-AMINO-PYRAZOLE COUPLING COMPONENT | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |