Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 9/20 | 0.69 |
| ▸ | RET | P07949 | 5/20 | 0.69 |
| ▸ | MET | P08581 | 3/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21750981 | 0.85 | KDR (0.61) | KDRRETMETEGFRAXL | |
| SCHEMBL21262601 | 0.85 | RET (0.70) | KDRRETFGFR2 | |
| SCHEMBL21793293 | 0.83 | KDR (0.61) | KDRRETMETEGFRAXL | |
| SCHEMBL21793294 | 0.83 | KDR (0.68) | KDRRETMETPDGFRA | |
| SCHEMBL22821317 | 0.82 | KDR (1.00) | KDRRET | |
| SCHEMBL21265684 | 0.82 | MET (0.81) | KDRRETMETEGFRFGFR2 | |
| SCHEMBL21246953 | 0.81 | KDR (0.59) | KDRRETMETEGFR | |
| SCHEMBL21793056 | 0.81 | RET (0.74) | KDRRETMETAXLPDGFRA | |
| SCHEMBL21793062 | 0.80 | RET (0.73) | KDRRETMETAXLPDGFRA | |
| SCHEMBL21262599 | 0.80 | KDR (1.00) | KDRRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019154133-A1 | DIOXAZOLINE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | 北京赛特明强医药科技有限公司 | 2019-08-15 | — | — | WO | disclosed |