Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 8/20 | 0.68 |
| ▸ | RET | P07949 | 5/20 | 0.68 |
| ▸ | MET | P08581 | 7/20 | 0.55 |
| ▸ | KIT | P10721 | 1/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4298086 | 0.83 | PDGFRA (0.77) | KDRMETKITPDGFRA | |
| SCHEMBL21265686 | 0.83 | KDR (0.69) | KDRRETMETPDGFRA | |
| SCHEMBL21792996 | 0.81 | RET (0.64) | KDRRETMETKITPDGFRA | |
| SCHEMBL21265684 | 0.81 | MET (0.81) | KDRRETMETKITPDGFRA | |
| SCHEMBL22821317 | 0.81 | KDR (1.00) | KDRRET | |
| SCHEMBL21793056 | 0.79 | RET (0.74) | KDRRETMETPDGFRA | |
| SCHEMBL21262599 | 0.79 | KDR (1.00) | KDRRET | |
| SCHEMBL21792906 | 0.79 | RET (0.73) | KDRRETMETPDGFRA | |
| SCHEMBL30664577 | 0.79 | KDR (1.00) | KDRRET | |
| SCHEMBL21793293 | 0.77 | KDR (0.61) | KDRRETMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020042972-A1 | UREA-SUBSTITUTED AROMATIC RING-LINKED DIOXANE AND QUINAZOLINE OR QUINOLINE COMPOUND, COMPOSITION AND APPLICATION THEREOF | 北京赛特明强医药科技有限公司 | 2020-03-05 | — | — | WO | disclosed |