SCHEMBL212667

SCHEMBL212667

[CH]1c2cc3ccccc3cc2-c2cc3ccccc3cc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.46
HSD17B10 Q99714 6/20 0.46
CASP1 P29466 4/20 0.46
HIF1A Q16665 4/20 0.46
CASP7 P55210 3/20 0.46
HPGD P15428 3/20 0.46
TSHR P16473 3/20 0.46
MAPK1 P28482 3/20 0.46
TP53 P04637 2/20 0.46
CYP2A6 P11509 6/20 0.39
ALOX12 P18054 1/20 0.39
NQO2 P16083 1/20 0.38
HBB P68871 2/20 0.37
CYP1A2 P05177 3/20 0.36
CYP3A4 P08684 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL217953 0.90 ALDH1A1 (0.44) ALDH1A1HSD17B10CASP1HIF1ACASP7
SCHEMBL814891 0.86 ALDH1A1 (0.41) ALDH1A1HSD17B10CASP1HIF1ACASP7
SCHEMBL1979202 0.77 ALDH1A1 (0.67) ALDH1A1HSD17B10CASP1HIF1ACASP7
SCHEMBL9042905 0.77 ALDH1A1 (0.67) ALDH1A1HSD17B10CASP1HIF1ACASP7
SCHEMBL1154675 0.77 ALDH1A1 (0.67) ALDH1A1HSD17B10CASP1HIF1ACASP7
SCHEMBL5917389 0.77 ALDH1A1 (0.67) ALDH1A1HSD17B10CASP1HIF1ACASP7
SCHEMBL28763536 0.77 ALDH1A1 (0.67) ALDH1A1HSD17B10CASP1HIF1ACASP7
SCHEMBL1811522 0.77 ALDH1A1 (0.67) ALDH1A1HSD17B10CASP1HIF1ACASP7
SCHEMBL816687 0.76 HSD17B10 (0.41) ALDH1A1HSD17B10CASP1HIF1ACASP7
SCHEMBL814555 0.76 MAPT (0.41) ALDH1A1HSD17B10CASP1HIF1ACASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11078311-B2 Single-site catalyst polyolefin polymerization process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-08-03 US claimed
US-9880469-B2 Resins for underlayers ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-01-30 US claimed
US-20160016872-A1 RESINS FOR UNDERLAYERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2016-01-21 US claimed
EP-0672675-A1 Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1995-09-20 EP claimed
US-5451649-A Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1995-09-19 US claimed
US-11708434-B2 Silica quenching agents for use in polymerization process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-07-25 US disclosed
WO-2023114813-A1 PROCESSES FOR MAKING PROPYLENE-BASED COPOLYMERS HAVING BROAD CDS AND MWDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-06-22 WO disclosed
US-11142593-B2 Lecithin quenching agent EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-10-12 US disclosed
US-20210277154-A1 Silica Quenching Agents for use in Polymerization Process EXXONMOBIL CHEMICAL PATENTS INC (US) 2021-09-09 US disclosed
US-11078311-B2 Single-site catalyst polyolefin polymerization process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-08-03 US disclosed
US-11046793-B2 Silica quenching agents for use in polymerization process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-06-29 US disclosed
US-11041029-B2 Aluminum alkyls with pendant olefins for polyolefin reactions EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-06-22 US disclosed
US-20050158864-A1 Analysis method EXXONMOBIL CHEMICAL PATENTS INC. 2005-07-21 US disclosed
US-20040220359-A1 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2004-11-04 US disclosed
US-20040138392-A1 polyolefin adhesives; to produce reactor blends (also called intimate blends) of various polymers and other polymer compositions. EXXONMOBIL CHEMICAL PATENTS INC. 2004-07-15 US disclosed
US-20040127614-A1 a Dot T-Peel of 1 Newton or more on Kraft paper; molecualr weight of 10,000 to 100,000; and a branching index (g') of 0.98 or less EXXONMOBIL CHEMICAL PATENTS INC. 2004-07-01 US disclosed
WO-2004046214-A2 MULTIPLE CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-06-03 WO disclosed
EP-1123938-A2 Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 2001-08-16 EP disclosed
EP-0672675-A1 Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1995-09-20 EP disclosed
US-5451649-A Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1995-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160016872-A1 RESINS FOR UNDERLAYERS AS3MT, TET2, MMAB ALDH1A1 3315/4885HSD17B10 1568/4885CASP1 3480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.