SCHEMBL217953

SCHEMBL217953

[CH]1c2ccccc2-c2cc3ccccc3cc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.44
HSD17B10 Q99714 6/20 0.44
HPGD P15428 4/20 0.44
TSHR P16473 3/20 0.44
MAPK1 P28482 3/20 0.44
CASP1 P29466 3/20 0.44
HIF1A Q16665 3/20 0.44
TP53 P04637 2/20 0.44
CASP7 P55210 2/20 0.44
L3MBTL1 Q9Y468 3/20 0.34
ATM Q13315 1/20 0.33
HBB P68871 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
BCHE P06276 1/20 0.32
POLB P06746 1/20 0.32
PTPRC P08575 1/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL814891 0.96 ALDH1A1 (0.41) ALDH1A1HSD17B10HPGDTSHRMAPK1
SCHEMBL212667 0.90 ALDH1A1 (0.46) ALDH1A1HSD17B10HPGDTSHRMAPK1
SCHEMBL816271 0.80 ALDH1A1 (0.54) ALDH1A1HSD17B10HPGDTSHRMAPK1
SCHEMBL18426 0.79 ALDH1A1 (0.44) ALDH1A1HSD17B10HPGDTSHRMAPK1
SCHEMBL27519715 0.76 ALDH1A1 (0.42) ALDH1A1HSD17B10HPGDTSHRMAPK1
SCHEMBL27485220 0.76 ALDH1A1 (0.42) ALDH1A1HSD17B10HPGDTSHRMAPK1
SCHEMBL27309984 0.76 ALDH1A1 (0.42) ALDH1A1HSD17B10HPGDTSHRMAPK1
SCHEMBL27667538 0.76 ALDH1A1 (0.42) ALDH1A1HSD17B10HPGDTSHRMAPK1
SCHEMBL27670655 0.76 ALDH1A1 (0.42) ALDH1A1HSD17B10HPGDTSHRMAPK1
SCHEMBL19136014 0.76 ALDH1A1 (0.42) ALDH1A1HSD17B10HPGDTSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114075214-B Organic compound, organic electroluminescent device and electronic device comprising the same 陕西莱特迈思光电材料有限公司 2023-07-14 CN claimed
US-20220131092-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-04-28 US claimed
CN-109906234-B Single site catalyst polyolefin polymerization process 埃克森美孚化学专利公司 2022-04-22 CN claimed
CN-114075214-A Organic compound, and organic electroluminescent device and electronic device comprising same 陕西莱特迈思光电材料有限公司 2022-02-22 CN claimed
US-20210328150-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-21 US claimed
CN-113493422-A Organic electroluminescent compound, organic electroluminescent material comprising same, and organic electroluminescent device 罗门哈斯电子材料韩国有限公司 2021-10-12 CN claimed
US-11078311-B2 Single-site catalyst polyolefin polymerization process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-08-03 US claimed
EP-0672675-A1 Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1995-09-20 EP claimed
US-5451649-A Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1995-09-19 US claimed
US-20240188424-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2024-06-06 US disclosed
US-20240174694-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-05-30 US disclosed
CN-117903127-A Organic electroluminescent compound, various host materials, and organic electroluminescent device comprising the same 罗门哈斯电子材料韩国有限公司 2024-04-19 CN disclosed
US-20240130230-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-04-18 US disclosed
US-11963439-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2024-04-16 US disclosed
EP-1123938-A2 Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 2001-08-16 EP disclosed
EP-0779765-B1 Hole-transporting material and use thereof TOYO INK MFG CO (JP) 2001-08-01 EP disclosed
US-6245449-B1 LIGHT EMITTER LAYERS OR ORGANIC COMPOUNDS, THIN LAYERS AND ELECTRODES, ANODES AND CATHODES TOYO INK MANUFACTURING CO., LTD. (JP) 2001-06-12 US disclosed
US-6150042-A ELECTROLUMINESCENCE DEVICE WITH HOLE INJECTING MATERIAL HAVING GOOD DURABILITY BEING A TRIPHENYLENE STRUCTURE OF GIVEN FORMULA HAVING MULTIPLE ETHER, SULFIDE, AND/OR AMINE SUBSTITUTIONS TOYO INK MANUFACTURING CO., LTD. (JP) 2000-11-21 US disclosed
EP-0847228-A2 Material for organoelectroluminescence device and use thereof TOYO INK MANUFACTURING CO., LTD. (JP) 1998-06-10 EP disclosed
EP-0779765-A2 Hole-transporting material and use thereof TOYO INK MANUFACTURING CO., LTD. (JP) 1997-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240174694-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME PIEZO1, SOD1, NECTIN4 ALDH1A1 533/4885HSD17B10 4122/4885HPGD 4510/4885
US-11963439-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same OR10J3, VDAC2, ICOSLG ALDH1A1 604/4885HSD17B10 2712/4885HPGD 3854/4885
US-20240188424-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, L1CAM, EPCAM ALDH1A1 767/4885HSD17B10 4501/4885HPGD 4643/4885
US-20240130230-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME L1CAM, TERT, ELAVL1 ALDH1A1 1113/4885HSD17B10 4685/4885HPGD 4562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.