Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.67 |
| ▸ | CASP1 | P29466 | 4/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 4/20 | 0.67 |
| ▸ | CASP7 | P55210 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | CYP2A6 | P11509 | 7/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9042905 | 1.00 | ALDH1A1 (0.67) | ALDH1A1HSD17B10CASP1HIF1AHPGD | |
| SCHEMBL1979202 | 1.00 | ALDH1A1 (0.67) | ALDH1A1HSD17B10CASP1HIF1AHPGD | |
| SCHEMBL28763536 | 1.00 | ALDH1A1 (0.67) | ALDH1A1HSD17B10CASP1HIF1AHPGD | |
| SCHEMBL5917389 | 1.00 | ALDH1A1 (0.67) | ALDH1A1HSD17B10CASP1HIF1AHPGD | |
| SCHEMBL1811522 | 1.00 | ALDH1A1 (0.67) | ALDH1A1HSD17B10CASP1HIF1AHPGD | |
| SCHEMBL9039265 | 0.93 | ALDH1A1 (0.68) | ALDH1A1HSD17B10CASP1HIF1AHPGD | |
| SCHEMBL16200967 | 0.87 | ALDH1A1 (0.55) | ALDH1A1HSD17B10CASP1HIF1AHPGD | |
| SCHEMBL30458681 | 0.84 | MEN1 (0.53) | ALDH1A1HSD17B10CASP1HIF1AHPGD | |
| SCHEMBL16144676 | 0.84 | MEN1 (0.53) | ALDH1A1HSD17B10CASP1HIF1AHPGD | |
| SCHEMBL19230417 | 0.84 | ALDH1A1 (0.52) | ALDH1A1HSD17B10CASP1HIF1AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563497-A | Catalyst component for olefin polymerization, preparation method, catalyst and application thereof | 中国石油化工股份有限公司 | 2021-10-29 | — | — | CN | claimed |
| CN-113563497-A | Catalyst component for olefin polymerization, preparation method, catalyst and application thereof | 中国石油化工股份有限公司 | 2021-10-29 | — | — | CN | disclosed |
| US-7884116-B2 | N-(pyridin-3-ylmethyl)-(2E,4E)-5-[(1S,2S,4aR,6R,7S,8S,8aS)-7-hydroxy-2,6,8-trimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]-2-methylpenta-2,4-dienamide, having cell adhesion molecule gene experssion inhibitory activty, used for treating inflammatory diseases, arthritis and as immunosuppressants | NIPPON SHINYAKU CO., LTD. (JP) | 2011-02-08 | — | — | US | disclosed |
| US-20070142539-A1 | Octahydronaphtalene derivative and medicine | NIPPON SHINYAKAU CO., LTD (JP) | 2007-06-21 | — | — | US | disclosed |
| EP-1702910-A1 | OCTAHYDRONAPHTHALENE DERIVATIVE AND MEDICINE | Nippon Shinyaku Co., Ltd. (JP) | 2006-09-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142539-A1 | Octahydronaphtalene derivative and medicine | ICAM1, VCAM1, CD40 | ALDH1A1 66/4885HSD17B10 1672/4885CASP1 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.