Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21268167 | 0.84 | SLC6A2 (0.40) | AURKATPX2EPHX2FAAHPIM1 | |
| SCHEMBL21268141 | 0.83 | MRGPRX4 (0.45) | MRGPRX4EPHX2FAAHNPC1GAA | |
| SCHEMBL21268338 | 0.79 | L3MBTL1 (0.46) | MRGPRX4MEN1NPC1GAARAB9A | |
| SCHEMBL31550001 | 0.79 | AURKA (0.56) | AURKATPX2MRGPRX4EPHX2FAAH | |
| SCHEMBL475754 | 0.79 | AURKA (0.56) | AURKATPX2MRGPRX4EPHX2FAAH | |
| SCHEMBL497707 | 0.78 | GPR3 (0.39) | AURKATPX2EPHX2PIM1MEN1 | |
| SCHEMBL4316500 | 0.76 | CA1 (0.50) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL21268229 | 0.75 | MRGPRX4 (0.42) | MRGPRX4MEN1NPC1RAB9AKMT2A | |
| SCHEMBL398487 | 0.73 | TSHR (0.45) | GAAALDH1A1TSHRHSD17B10PTGS2 | |
| SCHEMBL16961861 | 0.73 | AURKA (0.36) | AURKATPX2MRGPRX4EPHX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-B1 | HERBICIDAL AND FUNGICIDAL 3-PHENYLISOXAZOLIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-08-21 | — | — | EP | disclosed |