SCHEMBL2127248

SCHEMBL2127248

O=C(O)c1ccc(C(=O)c2ccccc2O)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIG1 P18858 1/20 0.74
SRD5A2 P31213 4/20 0.61
KDM4E B2RXH2 2/20 0.61
NAPRT Q6XQN6 2/20 0.61
HPGD P15428 2/20 0.61
CA12 O43570 1/20 0.61
ALDH1A1 P00352 1/20 0.61
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
HMGB1 P09429 1/20 0.61
CA4 P22748 1/20 0.61
CA6 P23280 1/20 0.61
CA7 P43166 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
CA9 Q16790 1/20 0.61
CA14 Q9ULX7 1/20 0.61
CYP2C8 P10632 1/20 0.58
CYP2C9 P11712 1/20 0.58
AKR1C3 P42330 3/20 0.57
STS P08842 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15477907 0.94 LIG1 (0.67) LIG1SRD5A2KDM4ENAPRTHPGD
SCHEMBL21802003 0.91 LIG1 (0.87) LIG1KDM4ENAPRTHPGDCA12
SCHEMBL29499085 0.91 LIG1 (0.87) LIG1KDM4ENAPRTHPGDCA12
Benzoic Acid SCHEMBL28785904 0.90 LIG1 (0.72) LIG1SRD5A2KDM4ENAPRTHPGD
SCHEMBL28027482 0.89 LIG1 (0.77) LIG1SRD5A2KDM4ENAPRTHPGD
SCHEMBL29390505 0.89 LIG1 (0.76) LIG1KDM4ENAPRTHPGDCA12
Benzene SCHEMBL6034371 0.89 LIG1 (0.76) LIG1KDM4ENAPRTHPGDCA12
SCHEMBL22129808 0.89 LIG1 (0.76) LIG1KDM4ENAPRTHPGDCA12
SCHEMBL36215 0.89 LIG1 (0.76) LIG1KDM4ENAPRTHPGDCA12
Phthalic Acid SCHEMBL11577907 0.88 AKR1C3 (0.76) LIG1KDM4ENAPRTHPGDCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0443742-B1 Presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 1997-10-01 EP claimed
US-5476754-A Presensitized; hydrophilic surface on substrate; light sensitive layer containing alkaline water-soluble photocrosslinkable copolycondensed diazo resin FUJI PHOTO FILM CO., LTD. (JP) 1995-12-19 US claimed
EP-0443742-A2 Presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1991-08-28 EP claimed
US-12559458-B2 Co-crystals or salts of psilocin and methods of treatment therewith Reset Pharmaceuticals, Inc. (US) 2026-02-24 US disclosed
EP-4486448-A1 CO-CRYSTALS OR SALTS COMPRISING PSILOCIN Reset Pharmaceuticals, Inc. (US) 2025-01-08 EP disclosed
US-20240383849-A1 CO-CRYSTAL OR SALT Reset Pharmaceuticals, Inc. 2024-11-21 US disclosed
CN-118871423-A Co-crystals or salts comprising xylometacin 雷塞特制药股份有限公司 2024-10-29 CN disclosed
US-12060328-B2 Co-crystals or salts of psilocybin and methods of treatment therewith Reset Pharmaceuticals, Inc. (US) 2024-08-13 US disclosed
WO-2023168023-A1 CO-CRYSTALS OR SALTS COMPRISING PSILOCIN Reset Pharmaceuticals, Inc. (US) 2023-09-07 WO disclosed
WO-2023168022-A1 CO-CRYSTALS OR SALTS COMPRISING PSILOCYBIN Reset Pharmaceuticals, Inc. (US) 2023-09-07 WO disclosed
US-20230279032-A1 CO-CRYSTAL OR SALT Reset Pharmaceuticals, Inc. 2023-09-07 US disclosed
EP-0397375-B1 Photosensitive composition and photosensitive lithographic printing plate KONISHIROKU PHOTO IND (JP) 1994-04-06 EP disclosed
US-5260161-A Developability after storage for long time, press life, and ink attachibility KONICA CORPORATION (JP) 1993-11-09 US disclosed
US-5250393-A Containing diazo resin and alkali metal or ammonium silicate FUJI PHOTO FILM CO., LTD. (JP) 1993-10-05 US disclosed
EP-0522457-A1 Photosensitive composition Mitsubishi Chemical Corporation (JP) 1993-01-13 EP disclosed
EP-0492959-A1 Method for developing presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1992-07-01 EP disclosed
EP-0487343-A1 Process for preparing a lithographic plate Fuji Photo Film Co., Ltd. (JP) 1992-05-27 EP disclosed
EP-0443742-A2 Presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1991-08-28 EP disclosed
EP-0415422-A2 Method for forming images FUJI PHOTO FILM CO., LTD. (JP) 1991-03-06 EP disclosed
EP-0397375-A1 Photosensitive composition and photosensitive lithographic printing plate KONICA CORPORATION (JP) 1990-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240383849-A1 CO-CRYSTAL OR SALT SLC6A3, SLC6A2, OPRK1 LIG1 2544/4885SRD5A2 2947/4885KDM4E 2287/4885
US-12060328-B2 Co-crystals or salts of psilocybin and methods of treatment therewith SLC6A3, SLC6A2, HTR2B LIG1 3192/4885SRD5A2 3130/4885KDM4E 2484/4885
US-20230279032-A1 CO-CRYSTAL OR SALT SLC6A3, SLC6A2, OPRK1 LIG1 2544/4885SRD5A2 2947/4885KDM4E 2287/4885
US-12559458-B2 Co-crystals or salts of psilocin and methods of treatment therewith SLC6A2, SLC6A4, SLC6A3 LIG1 3197/4885SRD5A2 2164/4885KDM4E 3143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.