Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409325 | 0.98 | MEN1 (0.41) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL795355 | 0.88 | MEN1 (0.41) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4279665 | 0.83 | GABRA1 (0.52) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL28231669 | 0.83 | MEN1 (0.43) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL28113278 | 0.81 | MEN1 (0.42) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8409006 | 0.81 | MEN1 (0.42) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL10405821 | 0.81 | NPSR1 (0.44) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8409324 | 0.80 | KMT2A (0.41) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| Fluoromethane SCHEMBL27938455 | 0.80 | ALDH1A1 (0.40) | CYP1A2CYP3A4TSHRSLC9A1ALDH1A1 | |
| Formic Acid SCHEMBL28234886 | 0.80 | KDM4E (0.39) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9452223-B2 | Materials and methods relating to glycosylation | GLYTHERA LIMITED (GB) | 2016-09-27 | — | — | US | claimed |
| EP-2442831-B9 | Materials and methods relating to glycosylation of a therapeutic polypeptide | GLYTHERA LTD (GB) | 2016-05-11 | — | — | EP | claimed |
| EP-2442831-B1 | Materials and methods relating to glycosylation of a therapeutic polypeptide | GLYTHERA LTD (GB) | 2015-11-04 | — | — | EP | claimed |
| CN-102481377-B | Materials and methods relating to glycosylation | THE UNIVERSITY OF BATH (GB) | 2014-10-29 | — | — | CN | claimed |
| US-20120190631-A1 | MATERIALS AND METHODS RELATING TO GLYCOSYLATION | Iksuda Therapeutics Limited (GB) | 2012-07-26 | — | — | US | claimed |
| CN-102481377-A | Materials and methods relating to glycosylation | UNIV BATH | 2012-05-30 | — | — | CN | claimed |
| EP-2442831-A2 | MATERIALS AND METHODS RELATING TO GLYCOSYLATION | The University Of Bath (GB) | 2012-04-25 | — | — | EP | claimed |
| WO-2010146362-A2 | MATERIALS AND METHODS RELATING TO GLYCOSYLATION | THE UNIVERSITY OF BATH (GB) | 2010-12-23 | — | — | WO | claimed |
| US-9452223-B2 | Materials and methods relating to glycosylation | GLYTHERA LIMITED (GB) | 2016-09-27 | — | — | US | disclosed |
| EP-2442831-B9 | Materials and methods relating to glycosylation of a therapeutic polypeptide | GLYTHERA LTD (GB) | 2016-05-11 | — | — | EP | disclosed |
| EP-2442831-B1 | Materials and methods relating to glycosylation of a therapeutic polypeptide | GLYTHERA LTD (GB) | 2015-11-04 | — | — | EP | disclosed |
| CN-102481377-B | Materials and methods relating to glycosylation | THE UNIVERSITY OF BATH (GB) | 2014-10-29 | — | — | CN | disclosed |
| US-20120190631-A1 | MATERIALS AND METHODS RELATING TO GLYCOSYLATION | Iksuda Therapeutics Limited (GB) | 2012-07-26 | — | — | US | disclosed |
| CN-102481377-A | Materials and methods relating to glycosylation | UNIV BATH | 2012-05-30 | — | — | CN | disclosed |
| EP-2442831-A2 | MATERIALS AND METHODS RELATING TO GLYCOSYLATION | The University Of Bath (GB) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010146362-A2 | MATERIALS AND METHODS RELATING TO GLYCOSYLATION | THE UNIVERSITY OF BATH (GB) | 2010-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190631-A1 | MATERIALS AND METHODS RELATING TO GLYCOSYLATION | NEU3, FUT5, NEU2 | MEN1 1699/4885KMT2A 2832/4885CYP1A2 3146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.