Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 8/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 8/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 2/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25882848 | 0.88 | PI4KA (0.55) | L3MBTL1MAPTGPR119PI4KAPI4K2B | |
| SCHEMBL21272848 | 0.81 | BRD4 (0.43) | L3MBTL1GAAMAPTNAMPTPI4KA | |
| SCHEMBL21272929 | 0.81 | L3MBTL1 (0.53) | L3MBTL1GAAMAPTNAMPTPOLB | |
| SCHEMBL5113125 | 0.80 | PI4KA (0.44) | L3MBTL1GPR119PI4KAPI4K2BPI4K2A | |
| SCHEMBL29484983 | 0.77 | L3MBTL1 (0.44) | L3MBTL1NAMPT | |
| SCHEMBL25882485 | 0.77 | L3MBTL1 (0.44) | L3MBTL1NAMPT | |
| SCHEMBL4640082 | 0.76 | FGFR1 (0.47) | FGFR1FGFR4HDAC6POLBMAPK1 | |
| SCHEMBL21821977 | 0.75 | DGAT1 (0.53) | DGAT1FGFR1FGFR4HDAC6PI4KA | |
| SCHEMBL30622708 | 0.75 | DGAT1 (0.53) | DGAT1FGFR1FGFR4HDAC6PI4KA | |
| SCHEMBL1408298 | 0.75 | DGAT1 (0.47) | DGAT1FGFR1FGFR4HDAC6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4026832-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7 | Almac Discovery Limited (GB) | 2022-07-13 | — | — | EP | disclosed |
| US-10766903-B2 | Piperidine derivatives as inhibitors of ubiquitin specific protease 7 | ALMAC DISCOVERY LIMITED (GB) | 2020-09-08 | — | — | US | disclosed |
| US-20190256518-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7 | GENETECH, INC. | 2019-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256518-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7 | USP7, USP5, UBA7 | DGAT1 4355/4885L3MBTL1 2081/4885FGFR1 4768/4885 |
| US-10766903-B2 | Piperidine derivatives as inhibitors of ubiquitin specific protease 7 | USP7, USP5, UBA7 | DGAT1 4355/4885L3MBTL1 2081/4885FGFR1 4768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.