SCHEMBL29764083

SCHEMBL29764083

Cc1cc(Nc2cc(Nc3ccc(N)c(C)c3)cc(Nc3ccc(N)c(C)c3)c2)ccc1N

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.71
TDP1 Q9NUW8 5/20 0.71
ALDH1A1 P00352 4/20 0.71
THRB P10828 2/20 0.71
ALOX15 P16050 2/20 0.71
RECQL P46063 1/20 0.71
HIF1A Q16665 1/20 0.71
TSHR P16473 3/20 0.50
GAA P10253 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
G6PD P11413 1/20 0.45
SOS1 Q07889 1/20 0.41
KDM4E B2RXH2 2/20 0.40
JAK2 O60674 1/20 0.40
S100B P04271 1/20 0.39
MAPK1 P28482 1/20 0.39
SKP2 Q13309 1/20 0.38
MAPK13 O15264 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29709 1.00 CYP3A4 (0.71) CYP3A4TDP1ALDH1A1THRBALOX15
SCHEMBL11511767 0.95 CYP3A4 (0.77) CYP3A4TDP1ALDH1A1THRBALOX15
SCHEMBL3655280 0.94 ALDH1A1 (0.65) CYP3A4TDP1ALDH1A1THRBALOX15
SCHEMBL22701365 0.87 ALDH1A1 (0.72) CYP3A4TDP1ALDH1A1THRBALOX15
SCHEMBL30998047 0.85 ALDH1A1 (0.70) CYP3A4TDP1ALDH1A1THRBALOX15
SCHEMBL2127369 0.85 ALDH1A1 (0.70) CYP3A4TDP1ALDH1A1THRBALOX15
SCHEMBL27438433 0.84 ALDH1A1 (0.54) CYP3A4TDP1ALDH1A1THRBALOX15
SCHEMBL28255467 0.84 CYP3A4 (0.68) CYP3A4TDP1ALDH1A1THRBALOX15
SCHEMBL8092870 0.84 TDP1 (1.00) CYP3A4TDP1ALDH1A1THRBALOX15
SCHEMBL23999865 0.82 ALDH1A1 (0.66) CYP3A4TDP1ALDH1A1THRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4077539-A1 THERMOPLASTIC MOULDING COMPOSITION CONTAINING POLYALKYLENE TEREPHTHALATE BASF SE (DE) 2022-10-26 EP disclosed
CN-114846080-A Thermoplastic molding compositions containing polyalkylene terephthalates 巴斯夫欧洲公司 2022-08-02 CN disclosed