SCHEMBL2127474

SCHEMBL2127474

CCCCCCCCCCNC(=O)C=CC(N)=O

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 3/20 0.59
ZDHHC2 Q9UIJ5 3/20 0.59
EGFR P00533 1/20 0.54
EPHX1 P07099 8/20 0.53
CASP2 P42575 1/20 0.48
HTR1A P08908 2/20 0.47
HTR2C P28335 2/20 0.47
HTR2A P28223 1/20 0.47
SLC6A4 P31645 1/20 0.47
HTR7 P34969 1/20 0.47
HTR6 P50406 1/20 0.47
APP P05067 1/20 0.47
NAAA Q02083 1/20 0.46
SPHK1 Q9NYA1 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30849149 1.00 ZDHHC20 (0.59) ZDHHC20ZDHHC2EGFREPHX1CASP2
SCHEMBL7047418 1.00 ZDHHC20 (0.59) ZDHHC20ZDHHC2EGFREPHX1CASP2
SCHEMBL11367039 1.00 ZDHHC20 (0.59) ZDHHC20ZDHHC2EGFREPHX1CASP2
SCHEMBL1824294 1.00 ZDHHC20 (0.59) ZDHHC20ZDHHC2EGFREPHX1CASP2
SCHEMBL5432087 1.00 ZDHHC20 (0.59) ZDHHC20ZDHHC2EGFREPHX1CASP2
SCHEMBL7882823 1.00 ZDHHC20 (0.59) ZDHHC20ZDHHC2EGFREPHX1CASP2
SCHEMBL7129938 1.00 ZDHHC20 (0.59) ZDHHC20ZDHHC2EGFREPHX1CASP2
SCHEMBL9461784 1.00 ZDHHC20 (0.59) ZDHHC20ZDHHC2EGFREPHX1CASP2
SCHEMBL7129948 1.00 ZDHHC20 (0.59) ZDHHC20ZDHHC2EGFREPHX1CASP2
SCHEMBL7564411 1.00 ZDHHC20 (0.59) ZDHHC20ZDHHC2EGFREPHX1CASP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8829116-B2 Method for producing block copolymers DOW GLOBAL TECHNOLOGIES LLC (US) 2014-09-09 US disclosed
US-8486428-B2 Compositions and methods for making and using acyclic N-halamine-based biocidal polymeric materials and articles BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2013-07-16 US disclosed
EP-2444426-B1 Method for producing block copolymers ROHM & HAAS (US) 2013-05-01 EP disclosed
US-20120101218-A1 METHOD FOR PRODUCING BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES LLC 2012-04-26 US disclosed
EP-2444426-A1 Method for producing block copolymers Rohm and Haas Company (US) 2012-04-25 EP disclosed
WO-2007126775-A2 COMPOSITIONS AND METHODS FOR MAKING AND USING ACYCLIC N-HALAMINE-BASED BIOCIDAL POLYMERIC MATERIALS AND ARTICLES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2007-11-08 WO disclosed
US-20070224161-A1 Compositions and methods for making and using acyclic N-halamine-based biocidal polymeric materials and articles BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2007-09-27 US disclosed
US-7008990-B2 Use of polymeric reaction product BASF AKTIENGESELLSCHAFT (DE) 2006-03-07 US disclosed
US-6902810-B1 Mesomorphic polyelectrolyte complexes prepared by reacting, in a liquid pahse a polymeric and oligomeric, anionic polyelectrolyte with a polymeric oligomeric, organic cationic polyelectrolyte and cationic surfactant BASF COATINGS AG (DE) 2005-06-07 US disclosed
US-6815498-B2 BLOCK POLYMERS BASF AKTIENGESELLSCHAFT (DE) 2004-11-09 US disclosed
US-6790909-B2 INITIATOR FUNCTIONS SUITABLE FOR CATIONIC POLYMERIZATION INTO THE MACROINITIATOR. EXAMPLES OF SUCH INTERESTING INITIATOR FUNCTIONS ARE GROUPS CONTAINING HALOGEN OR SULFONYL CHLORIDE BASF AKTIENGESELLSCHAFT (DE) 2004-09-14 US disclosed
US-6716905-B1 AQUEOUS DISPERSION OF A STILBENE DERIVATIVE POLYMER MADE USING A FREE RADICAL CATALYST COATINGS AG (DE) 2004-04-06 US disclosed
US-20040034182-A1 Method for the production of a polymerisation reaction product BASF AKTIENGESELLSCHAFT (DE) 2004-02-19 US disclosed
US-20040024145-A1 Graft copolymers, their preparation and their use BASF AKTIENGESELLSCHAFT (DE) 2004-02-05 US disclosed
US-20040014872-A1 Bonding agent composition containing solid matter, with radically polymerised block copolymers BASF AKTIENGESELLSCHAFT (DE) 2004-01-22 US disclosed
US-20030170306-A1 Use of polymeric reaction product BASF AKTIENGESELLSCHAFT (DE) 2003-09-11 US disclosed
US-20030018137-A1 Method for producing a polymeric conversion product BASF AKTIENGESELLSCHAFT (DE) 2003-01-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070224161-A1 Compositions and methods for making and using acyclic N-halamine-based biocidal polymeric materials and articles NAAA, NIT2, AADAC ZDHHC20 308/4885ZDHHC2 1095/4885EGFR 1063/4885
US-20030170306-A1 Use of polymeric reaction product OXSR1, OGFR, CBR1 ZDHHC20 3928/4885ZDHHC2 3692/4885EGFR 962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.