Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.47 |
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.47 |
| ▸ | ADCY5 | O95622 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18176944 | 0.85 | ADORA2A (0.43) | ADORA2ATMIGD3ADORA1ADCY5HDAC1 | |
| SCHEMBL18176956 | 0.78 | ADORA2A (0.49) | ADORA2ATMIGD3ADORA1ADCY5HDAC1 | |
| SCHEMBL18179484 | 0.77 | ADORA2A (0.49) | ADORA2ATMIGD3ADORA1ADCY5HTT | |
| SCHEMBL18176940 | 0.77 | ADORA2A (0.48) | ADORA2ATMIGD3ADORA1ADCY5HDAC1 | |
| SCHEMBL18176934 | 0.76 | TMIGD3 (0.42) | ADORA2ATMIGD3ADORA1ADCY5HDAC1 | |
| SCHEMBL18179481 | 0.74 | TMIGD3 (0.41) | ADORA2ATMIGD3ADORA1ADCY5HDAC1 | |
| SCHEMBL18176935 | 0.74 | TMIGD3 (0.41) | ADORA2ATMIGD3ADORA1ADCY5HDAC1 | |
| SCHEMBL24547860 | 0.73 | ADORA2A (0.53) | ADORA2ATMIGD3ADORA1ADCY5HDAC1 | |
| SCHEMBL18176939 | 0.71 | TMIGD3 (0.44) | ADORA2ATMIGD3ADORA1HDAC1HDAC2 | |
| SCHEMBL26729700 | 0.71 | ADORA2A (0.51) | ADORA2ATMIGD3ADORA1ADCY5HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10385090-B2 | Nucleotide derivative or salt thereof, nucleotide-derived 5′-phosphate ester or salt thereof, nucleotide-derived 3′-phosphoramidite compound or salt thereof, and polynucleotide | NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY (JP) | 2019-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10385090-B2 | Nucleotide derivative or salt thereof, nucleotide-derived 5′-phosphate ester or salt thereof, nucleotide-derived 3′-phosphoramidite compound or salt thereof, and polynucleotide | SLC34A1, SLC34A2, SLC34A3 | ADORA2A 511/4885TMIGD3 4335/4885ADORA1 132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.